期刊：
Journal of the Science of Food and Agriculture,2024年104(6) ISSN：0022-5142
通讯作者：
Du, Jing;Zhang, WN
作者机构：
[Zhang, Wei-nong; He, Jun-bo; Du, Jing; Zhang, Hai-long] Wuhan Polytech Univ, Key Lab Deep Proc Major Grain & Oil, Minist Educ, Wuhan, Peoples R China.;[Du, Jing; Zhang, Wei-nong; Zhang, WN] Wuhan Polytech Univ, Key Lab Deep Proc Major Grain & Oil, Minist Educ, Wuhan 430023, Peoples R China.;[Zhang, Wei-nong; He, Jun-bo; Du, Jing; Zhang, Hai-long] Wuhan Polytech Univ, Hubei Key Lab Proc & Transformat Agr Prod, Wuhan, Peoples R China.;[Zhang, Wei-nong; He, Jun-bo; Wang, Kun-li; Du, Jing; Zhang, Hai-long; Wang, Zhi-xian] Wuhan Polytech Univ, Coll Food Sci & Engn, Wuhan, Peoples R China.;[Zhang, Wei-nong; He, Jun-bo; Zhang, WN; Zhang, Hai-long] Engn Res Ctr Lipid Based Fine Chem Hubei Prov, Wuhan, Peoples R China.
通讯机构：
[Du, J; Zhang, WN ] W;Wuhan Polytech Univ, Key Lab Deep Proc Major Grain & Oil, Minist Educ, Wuhan 430023, Peoples R China.;Engn Res Ctr Lipid Based Fine Chem Hubei Prov, Wuhan, Peoples R China.
关键词：
French fries;oil absorbency;rice bran oil;γ-oryzanol
摘要：
BACKGROUND: The aim of this research was to evaluate the possibility of lipid concomitant gamma-oryzanol reducing oil absorbency of fried foods and the underlying mechanism. Therefore, the influence of gamma-oryzanol on moisture and oil content, and distribution and micromorphology of French fries and the viscosity, fatty acid composition and total polar compounds content of rice bran oil (RBO) after frying were studied.RESULTS: Our results showed that the incorporation of low concentration of gamma-oryzanol [low addition group (LAG)] (5.754 g/kg) decreased the oil absorbency and porous structure of French fries during frying. Additionally, LAG incorporation inhibited the degradation of linoleic acid, decreased the growth rate of saturated fatty acids, total polar compounds and viscosity of frying oil.CONCLUSIONS: Consequently, it was recommended to incorporate a small amount of gamma-oryzanol in frying oil because it could inhibit oil absorption behavior of French fries. (c) 2023 Society of Chemical Industry.
作者机构：
[He, Dongping; Gao, Pan; Liu, Ying; Gao, P; Yin, Jiaojiao; Zhong, Wu; Huang, Chuanyang; Hu, Chuanrong] Wuhan Polytech Univ, Coll Food Sci & Engn, Key Lab Edible Oil Qual & Safety State Market Regu, Key Lab Deep Proc Major Grain & Oil,Minist Educ Ch, Wuhan, Peoples R China.;[Wang, Shu] Wuhan Inst Food & Cosmet Control, Key Lab Edible Oil Qual & Safety State Market Reg, Wuhan, Peoples R China.;[Wang, Xingguo] Jiangnan Univ, Sch Food Sci & Technol, Int Joint Res Lab Lipid Nutr & Safety, Wuxi, Peoples R China.
通讯机构：
[Gao, P ] W;Wuhan Polytech Univ, Coll Food Sci & Engn, Key Lab Edible Oil Qual & Safety State Market Regu, Key Lab Deep Proc Major Grain & Oil,Minist Educ Ch, Wuhan, Peoples R China.
关键词：
Iron walnut oil;Oleogels;Fatty acid composition
摘要：
In this study, we compared the quality of iron walnut oil (IWO) oleogels prepared with different oleogelators, including gamma-oryzanol/beta-sitosterol (OZ-PS), gamma-oryzanol/triglyceride (OZ-TC), monoglycerides (MGS), beeswax (BW), beeswax-monoglycerides (BW-MGS), and carnauba wax (CW). The physicochemical and component properties, rheological and textural parameters, macroscopic morphologies, and antioxidant capacities of the resulting oleogels were analyzed. In addition, their microscopic properties were analyzed using Fouriertransform infrared (FTIR), X-ray powder diffraction (XRD) spectroscopy, and polarized light microscopy (PLM). The results showed that the gel structures produced by different oleogelators did not change the fatty acid composition of IWO. In addition, the IWO oleogel prepared with OZ-PS had a more stable network structure, excellent hardness at 4celcius (1116.51 g), better antioxidant capacity (766.50 mu mol TE/kg) and higher total phenolic content (14.98 mg/kg) than any other experimental IWO oleogels. Moreover, comprehensive ranking by principal component analysis of numerous characteristics showed that the OZ-PS oleogel (2.533) ranked first among the six oleogels studied. Therefore, the IWO oleogel prepared with OZ-PS is a promising product, and our results provide guidance for the preparation of IWO oleogels, such as to increase their applications in the food industry.
摘要：
Anthocyanin extracts from purple tomato (PTA) were incorporated with polyvinyl alcohol (PVA), resulting in a series of colorimetric PVA/PTA films with PTA concentrations of 0%, 1%, 3%, and 5% (based on PVA). The role of anthocyanin on color response, Fourier-transform infrared (FTIR), thickness, water content, mechanical properties, antioxidant activity, and water vapor permeability (WVP) through the films was examined. In addition, its application in smart packaging to assess the freshness of shrimp was studied. It was found that the tensile strength, contact angle and WVP of PVA/PTA films increases with the addition of more PTA, while the elongation at break and water content decreased. FTIR analysis showed that there are interactions between PTA and the PVA matrix. The addition of anthocyanins caused significant improvement in the antioxidant properties of PVA films. Furthermore, the total volatile alkaline nitrogen (TVB-N), total plate count (TPC), and pH value of shrimp were monitored after 4 days of refrigeration, and the color change of the indexes was recorded. The PVA/PTA films changed color from purple to yellow-green during the storage time of 0-4 days for shrimp. This suggests that the film could be used in smart packaging as a real-time freshness indicator for shrimp.
摘要：
The recovery of Au(III) has become a focal point of interest due to its significance in resource utilization and addressing environmental contamination. In this study, [C(3)NH(2)Mim]Cl-CMPS and PPh3-CMPS were successfully developed by immobilizing [C(3)NH(2)Mim]Cl and triphenylphosphine (PPh3) onto chloromethylated polystyrene beads (CMPS). The adsorbents demonstrated consistently high adsorption efficiency (>95 %) at a wide pH range. The [C(3)NH(2)Mim]Cl-CMPS and PPh3-CMPS exhibited exceptional selective adsorption ability for Au(III), and the adsorption process adhered to the PSO and Langmuir model. The adsorption efficiency of Au(III) remained constant after five consecutive cycles, highlighting outstanding reusability performance. Furthermore, as the existence of multiple coexisting metal ions, [C(3)NH(2)Mim]Cl-CMPS and PPh3-CMPS could efficiently and selectively capture Au(III) from the gold slag and PCBs lixivium, which is promising for Au recovery in practice.
摘要：
adipate terephthalate (PBAT) as matrix and zinc oxide nanoparticles (ZnONPs) and silver nanoparticles (AgNPs) as antibacterial agents, a series of antibacterial PLA/PBAT films were prepared by melt blending. The weight ratio of PLA, PBAT and nanoparticles in composite films was 70:900:10 (lower loading) or 70:900:20 (higher loading). The results showed that comparing with the PLA/PBAT films, the hydrophilicity, oxygen barrier properties, mechanical performance and antibacterial activities of PLA/PBAT/nanoparticles films were significantly improved (P < 0.05), and influenced by the content and type of nanoparticles. After the addition of nanoparticles, the maximum change of films performance was from 71.3 degrees to 35.8 degrees for water contact angle, from 7.4 x 10(-14) cm(3) cm.cm(-2). s(-1). Pa-1 to 5.5 x 10(-14) cm(3) cm.cm(-2). s(-1). Pa-1 for oxygen transmission permeability, from 26.4 MPa to 31.4 MPa for tensile strength, and from 0% to 57.8% (Escherichia coli) or 58.6% (Staphylococcus aureus) for antibacterial ratio. The films with higher loading content of nanoparticles showed a better antibacterial activity. For the same nanoparticles content, the antibacterial activity of PLA/PBAT/AgNPs was better than PLA/PBAT/ZnONPs. The overall migration in food simulants involving acetic acid (3%) ethanol (10% and 95%) was below 10 mg/dm(2) for most films, however, the overall migration for the films with higher content of AgNPs exceeded the limit value. The fresh noodles packaged by PLA/PBAT/AgNPs films showed the significant lowest total viable count with 4.6 lg (CFU/g) and the best appearance color characterized by L* (lightness), a*(red-green) and b*(yellow-blue) at storage time of 7 d in contrast with PLA/PBAT and PLA/PBAT/ZnONPs films, indicating the potential application of prepared films in active packaging to prolong the shelf life of food.
通讯机构：
[Shen, SN ; Li, H ; Li, H] W;Wuhan Univ, Sch Power & Mech Engn, Wuhan 430072, Peoples R China.;Wuhan Polytech Univ, Sch Mech Engn, Wuhan 430048, Peoples R China.
关键词：
Laser powder bed fusion;Laser ultrasonic detection;Surface roughness;Internal holes;Longitudinal wave
摘要：
In view of the non-destructive and non-contact features, laser ultrasonic (LU) technology has long been the effective method to detect tiny defects for laser powder bed fusion (LPBF) additive manufactured specimens. Of larger concern is the variation and the corresponding mechanism on tested results of LU detection as the property of LPBF additive manufactured specimen is changed. Aiming at the property of surface roughness, this work investigated the propagation characteristics of excited ultrasonic waves in LPBF additive manufactured 316L stainless steel with different surface roughness, as well as the interaction between ultrasonic waves and artificial submillimeter holes. Both numerical simulated and experimental study were conducted. Simulated results revealed that the amplitudes of longitudinal wave (L wave) and its echo wave L1 at the holes exhibited a discernible increase as the surface was coarser. The increase in surface roughness was detrimental to the resolution of defect detection as was expected from the increased amount of noise. LPBF fabrication and the subsequent LU pulse-echo detection were conducted for 316L stainless steel. Both B-scan and C-scan were able to detect the holes with the diameter of 0.6 mm. The speckle phenomenon deriving from the increase in surface roughness emerged, corresponding to the increased ultrasonic signal energy but deteriorated resolution of detected images. It is feasible to optimize LU detected effect by minimize the surface roughness of tested specimens.
摘要：
Poly (ethylene oxide) (PEO) is a potential material for solid-state lithium batteries. However, the present polymer electrolyte is hampered by its low ionic conductivity at room temperature and poor mechanical properties, which are significant barriers to its practical application. Herein, we designed a high-performance composite solid electrolyte (PLSP) by incorporating PEO, LiTFSI, and the solid plasticizer butanedinitrile into a 3D polyethylene terephthalate (PET) nonwoven framework with excellent mechanical properties. The PLSP achieved an impressive ionic conductivity of 5.45 x 10-4S cm-1, nearly 100 times higher than the original PEO electrolyte (6.1 x 10-6 S cm -1) at room temperature. Additionally, the optimized composite electrolyte exhibited an extended electrochemical window of up to 5.2 V vs. Li+/Li and a remarkable tensile strength exceeding 8.55 MPa. The stability of the lithium symmetrical battery's charge and discharge voltage platform after 400 h of cycling indicated favorable interfacial compatibility between the PLSP and lithium metal. Furthermore, the assembled Li/PLSP/LFP configuration displayed a discharge specific capacity of 131.4 mA h g-1 and a capacity retention of 93.8 % after 100 cycles at 1C at room temperature, highlighting the promising potential of the composite electrolyte for solid-state lithium batteries.
摘要：
Environmental pollution caused by ciprofloxacin is a major problem of global public health. A machine learning-assisted portable smartphone-based visualized molecularly imprinted electrochemiluminescence (MIECL) sensor was developed for the highly selective and sensitive detection of ciprofloxacin (CFX) in food. To boost the efficiency of electrochemiluminescence (ECL), oxygen vacancies (OVs) enrichment was introduced into the flower-like Tb@Lu(2)O(3) nanoemitter. With the specific recognition reaction between MIP as capture probes and CFX as detection target, the ECL signal significantly decreased. According to, CFX analysis was determined by traditional ECL analyzer detector in the concentration range from 5×10(-4) to 5×10(2)μmolL(-1) with the detection limit (LOD) of 0.095nmolL(-1) (S/N=3). Analysis of luminescence images using fast electrochemiluminescence judgment network (FEJ-Net) models, achieving portable and intelligent quick analysis of CFX. The proposed MIECL sensor was used for CFX analysis in real meat samples and satisfactory results, as well as efficient selectivity and good stability.
摘要：
The current study investigated the impact of ascorbic acid (AA) on physicochemical and emulsifying properties of highland barley protein (HBP). Emulsifying and solubility of AA-modified HBP increased compared to its native state. However, excessive AA concentration induced protein reaggregation, leading to a deterioration of these properties. At a concentration of 0.3 % (w/v) AA, the highland barley protein emulsion (HBPE) exhibited the smallest average particle size (0.59 mu m), and the protein demonstrated superior emulsification properties. The observed alterations stem from the formation of covalent bonds between HBP and AA through the Maillard reaction. These changes also relate to modifications in the secondary structure, marked by a notable increase of 60.25 % in beta-turns, accompanied by reductions of 16.45 % in alpha-helices and 33.84 % in beta-sheets. This was confirmed through analyses of disulfide bond content and FTIR. The outcomes of this study hold promise for enhancing the stability of emulsion formulations based on HBP, achieved by harnessing the complex formation between HBP and AA.
摘要：
In this work, hydrogel beads with 3D network structure were successfully prepared using montmorillonite nanosheets (MMTNS) combined with macromolecule polymers. Batch adsorption tests revealed that the increase in exfoliation degree of MMTNS was beneficial to improve the methylene blue (MB) adsorption on hydrogel beads (HB). In addition, the HB with 25 % MMTNS-3 dosage achieved high mechanical strength and reached the maximum adsorption capacity of 543.1 mg/g. Effects of MB concentration (40-120 mg/L), adsorbent dosage (1-1.5 g) and flow rate (5-15 mL/min) on fixed -bed column adsorption indicated that the HB column exhibited an excellent dynamic adsorption performance and recycling performance, much better than the D113 resin. The good fits of Pseudo -first -order model and Pseudo -second -order model and a better Langmuir model fitting result implied a monolayer chemical adsorption and physical adsorption nature of MB on HB. Moreover, scanning electron microscope combined with the energy dispersive spectrometer, fourier transform infrared spectroscope and X-ray photoelectron spectroscopy measurements indicated that the adsorption mechanism was mainly attributed to Ca ion -exchange and chemical bonding of -COOH and -OH groups with MB. Such hydrogel beads showed a good potential in the application of practical wastewater treatment.
摘要：
Hybrid composites are widely regarded as the most promising choice for anode material in sodium -ion batteries. However, integrating high capacity and excellent cyclic stability into composites remains challenging. This work demonstrates a thin -liquid -layer polymerization approach to fabricate an integrated porous polypyrrole/carbon composite (PPy/C) for a high-performance sodium storage anode. By adjusting the monomer concentration reasonably and combining with heterostructure engineering, the optimized PPy/C was used as the anode for sodium -ion batteries, achieving rapid electrochemical kinetics and satisfactory reversible capacity. The reaction mechanism between PPy and Na+ in the Faraday reaction was revealed by ex -situ electrochemical impedance spectroscopy (EIS). DFT calculations illustrate that the synergistic effect between porous carbon and PPy can regulate the electron transfer mode around Na atoms, which contributes to anchoring Na in the PPy/C composite structure. Moreover, the PPy/C offers an ultrahigh capacity of 552 mA h g-1 at 0.1 A g-1 and a capacity retention rate of 86.5 % after 200 cycles. A full cell assembled with PPy/C and Na3V2(PO4)3 demonstrates a high energy density of 243.1 W h kg-1 at 125 W kg- 1 power density. This work would offer valuable thought for advancing the practical application of conductive polymer/carbon composites.
摘要：
The photocatalytic valorization of glucose has attracted more and more attention for producing value-added chemicals. Herein, value-added chemicals like arabinose and formic acid were obtained by selective photocatalytic oxidation of glucose irradiated with visible light, which was realized using Bi2O3/TiO2 composite as the photocatalyst and atmospheric O2 as the oxidant in water. It was found that the photocatalytic performance of Bi2O3/TiO2 composite in the glucose oxidation was obviously superior to that of pure Bi2O3 and pure TiO2, the significantly enhanced photocatalytic efficiency was mainly attributed to the promotion of photogenerated charge separation and adsorption capacity towards glucose. The influences of mass ratio of Bi2O3 to TiO2 and initial concentration of glucose on the glucose oxidation were further investigated with many details. Additionally, recycling experiments showed that the Bi2O3/TiO2 composite exhibited a favorable stability in the photocatalytic process, and the roles of various active species for glucose oxidation were also determined by the active species trapping experiments. This work could provide some valuable viewpoints for producing value-added chemicals from biomass by photocatalysis.
摘要：
Weeds are a significant threat to agricultural productivity and the environment. The increasing demand for sustainable weed control practices has driven innovative developments in alternative weed control technologies aimed at reducing the reliance on herbicides. The barrier to adoption of these technologies for selective in-crop use is availability of suitably effective weed recognition. With the great success of deep learning in various vision tasks, many promising image-based weed detection algorithms have been developed. This paper reviews recent developments of deep learning techniques in the field of image-based weed detection. The review begins with an introduction to the fundamentals of deep learning related to weed detection. Next, recent advancements in deep weed detection are reviewed with the discussion of the research materials including public weed datasets. Finally, the challenges of developing practically deployable weed detection methods are summarized, together with the discussions of the opportunities for future research. We hope that this review will provide a timely survey of the field and attract more researchers to address this inter-disciplinary research problem.
作者机构：
[Xia, Yang; Ho, Wingkei] Educ Univ Hong Kong, Dept Sci & Environm Studies, Tai Po, Hong Kong 999077, Peoples R China.;[Xia, Yang; Ho, Wingkei] Educ Univ Hong Kong, Ctr Environm & Sustainable Dev CESD, Tai Po, Hong Kong 999077, Peoples R China.;[Zhu, Bicheng; Yu, Jiaguo; Yu, JG] China Univ Geosci, Fac Mat Sci & Chem, Lab Solar Fuel, Wuhan 430074, Peoples R China.;[Xia, Yang] Wuhan Inst Technol, Sch Chem Engn & Pharm, Minist Educ, Key Lab Green Chem Proc, Wuhan 430205, Peoples R China.;[Ho, Wingkei] City Univ Hong Kong, State Key Lab Marine Pollut, Kowloon, Tat Chee Ave, Hong Kong, Peoples R China.
通讯机构：
[Ho, WK ] E;[Yu, JG ] C;Educ Univ Hong Kong, Dept Sci & Environm Studies, Tai Po, Hong Kong 999077, Peoples R China.;Educ Univ Hong Kong, Ctr Environm & Sustainable Dev CESD, Tai Po, Hong Kong 999077, Peoples R China.;China Univ Geosci, Fac Mat Sci & Chem, Lab Solar Fuel, Wuhan 430074, Peoples R China.
摘要：
Sluggish charge kinetics and moderate adsorption-desorption ability of gas molecules are major limitations for photocatalytic NOx elimination of bulk g-C3N4. A hierarchical porous g-C3N4 photocatalyst modified with N vacancies and charge channels (KCNN) was prepared by thermal polymerisation in KCl medium followed by quenching to increase the photocatalytic efficiency. The optimized KCNN sample exhibits highly enhanced photocatalytic NO removal rate (70.5%), which is superior to those of bulk g-C3N4 (38.1%), porous g-C3N4 (54.5%) and K-doped g-C3N4 (58.6%), respectively. X-ray photoelectron spectroscopy and electron paramagnetic resonance data reveal the successful formation of N vacancy in g-C3N4 framework. The enhanced activity of KCNN is ascribed to the enlarged surface area, expanded light absorption, low charge recombination efficiency and strong oxidation capability, respectively. In situ DRIFTS and density functional theory results suggest that the introduction of N vacancies and K+ ions enable control over NO adsorption and activation, leading to the implementation of a preferred pathway (NO -> NO+ -> NO3-) and reduction in the emission of toxic in-termediates. This work presents a potential idea for improving the charge transfer of layered materials and optimising the diffusion/adsorption/activation of gas molecules for photocatalytic NO oxidation.
作者机构：
[Cai, Jie; Xie, F; Xie, Fang; Zhang, Die] Wuhan Polytech Univ, Natl R&D Ctr Se Rich Agr Prod Proc, Hubei Engn Res Ctr Deep Proc Green Se Rich Agr Pro, Sch Modern Ind Selenium Sci & Engn, Wuhan 430023, Peoples R China.;[Cai, Jie; Zhang, Die] Wuhan Polytech Univ, Key Lab Deep Proc Major Grain & Oil, Hubei Key Lab Proc & Transformat Agr Prod, Minist Educ, Wuhan 430023, Peoples R China.
通讯机构：
[Cai, J; Xie, F ] W;Wuhan Polytech Univ, Natl R&D Ctr Se Rich Agr Prod Proc, Hubei Engn Res Ctr Deep Proc Green Se Rich Agr Pro, Sch Modern Ind Selenium Sci & Engn, Wuhan 430023, Peoples R China.
摘要：
To investigate crack propagation and the coalescence mechanism of a rock bridge under unloading condition induced by intensive excavation of rock mass, the direct shear test with unloading normal stress and corresponding particle flow code (PFC) simulation were conducted on the sandstone specimen containing a parallel fissure pair considering different fissure inclinations (varied from 0 degrees to 90 degrees) and initial shear stresses (varied from 4 to 7 MPa). Three failure patterns (i.e., shear failure, tensile failure, and tensile-shear mixed failure) are identified as experimental and numerical results. The failure pattern transforms in the order of a shear, tensile, and tensile-shear mixed failure pattern as the fissure inclination increases. Three displacement field types are summarized and correspond to different failure patterns. Comparing the shear strength, cracking process, and microscopic displacement field in the direct shear test with unloading normal stress and the conventional direct shear test, normal unloading weakens the shear strength of the specimen under the selected stress conditions (initial normal stress is 20 MPa, initial shear stress ranges from 4 to 7 MPa). Rebound deformation in the process of unloading promotes the high proportion of tensile cracks for the tested fissure inclinations.
摘要：
The contribution systematically reviews the conceptual proposition, mechanism, catalyst species, applications, existing controversies and future developmental trends of self-immobilized polyolefin catalysts (SIPCs). To avoid the adverse effects in heterogenization of single site catalysts, the concept of self-immobilization was designed in order to not only keep the single site characteristics of catalysts but also improve polyolefin morphology control to reliver reactor fouling. The self-immobilized polyolefin catalysts have extended their territory from early-transition-metal to late-transition-metal ones, and been applied to produce high value-added polyolefins. Due to the lack of direct evidences, the classic self-immobilization mechanism invokes huge controversies, and the nature of self-immobilization needs to be explored in depth and explained by a more insightful theory. Fortunately, the self-immobilized polyolefin catalysts have been developed into the flexible immobilization modes of more robust product morphology control.
摘要：
The work aimed to explore the effect of supercritical carbon dioxide (SCCD) treatment on the enzyme activity, color, carotenoid, sugar and phenolic profile, and antioxidant activity of fresh-cut pumpkins. The polyphenol oxidase (PPO) and peroxidase (POD) activities of SCCD-treated pumpkin cubes were reduced by 21% and 18%, respectively. The lightness value of SCCD-treated samples declined compared to the untreated samples, whereas the redness and yellowness values in treated samples were enhanced. The lutein, alpha-carotene, beta-carotene and total carotenoids, glucose, sorbitol, and other polysaccharides in the SCCD-treated samples showed a fluctuation trend. Similarly, the treated sample's total phenolic contents (TPC), ABTS (2,2 '- azino-bis(3ethylbenzothiazoline-6-sulfonic acid, DPPH (2,2-diphenyl-1-picrylhydrazyl), and superoxide radical scavenging activities were increased and then reduced. An enhancement was noted in the coumaryloquinic acid I and II, caffeic acid glucoside, 4-hydroxybenzoic acid, and p-coumaric acid of SCCD-treated samples. The work demonstrated that the SCCD technique at moderate conditions could obtain higher retention of nutritional composition in fresh -cut pumpkins.
摘要：
Ultrasound (US)-mediated sonodynamic therapy (SDT) has received extensive attention in pathogen elimination for non-invasiveness and high spatial and temporal accuracy. Considering that hydrogel can provide a healing-friendly environment for wounds, in this work, hybrid hydrogels are constructed by embedding Ag doped TiO(2) nanoparticles in chitosan-polyvinyl alcohol hydrogels for enhanced sonodynamic antibacterial therapy. With metal silver doped, TiO(2) nanoparticles sonosensitivity is improved to generate more reactive oxygen species (ROS), which endows hybrid hydrogels with high-efficient antibacterial properties. In vivo results show that hybrid hydrogel dressing can prevent infection and promote wound closure within 2days. The healing ratio excess 95% with no pus produced at the end of treatment. The therapeutic mechanism was identified that heterojunction formed in Ag doped TiO(2) facilitates the separation of charge carriers under US irradiation, leading to elevating ROS generation. The generated ROS promote hybrid hydrogels sonodynamic antibacterial therapeutic efficacy to thoroughly eliminate pathogen via disrupting bacterial cell membrane integrity, decreasing membrane fluidity and increasing membrane permeability. Besides, biofilm formation could be effectively inhibited. This work developed a hybrid hydrogel with amplified SDT effect for wound healing, which is expected to provide inspiration of hybrid hydrogels design and Ti-based nanomaterials sonosensitivity enhancement.
