作者：
Wu, Dingwei;Tao, Suwan;Zhu, Lian;Zhao, Chenchen;Xu, Na
期刊：
ACS Applied Bio Materials,2024年7(2):1125-1134 ISSN：2576-6422
作者机构：
[Tao, Suwan; Zhao, Chenchen; Xu, Na; Wu, Dingwei] Institute of Biology and Medicine, College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan 430065, China;[Zhu, Lian] School of Chemical and Environmental Engineering, Wuhan Polytechnic University, Wuhan 430023, China;[Zhao, Chenchen] School of Basic Medical Sciences, Jinzhou Medical University, Jinzhou 121000, China
摘要：
Cutaneous trauma repair is still a challenge in the clinic due to the scar formation and slow healing rate, especially for diabetic patients. Various drug-loading wound dressings have been explored to solve this problem. Mesenchymal stem cell (MSC)-derived exosomes have been considered as a potential cell-free drug because of their anti-inflammation function and tissue repair property that are comparable to that of MSCs. Herein, a composite wound dressing (Exo/Gel) consisting of the chitosan hydrogel and adipose MSC-derived exosome (ADMSC-Exo) was designed and fabricated by a physical mixing method to promote the skin full-thickness wound repair. The exosomes were slowly released from the Exo/Gel dressing with the degradation of the chitosan hydrogel. The Exo/Gel displayed enhanced cell migration and angiogenic properties in vitro. And the results in the rat skin wound model showed that the Exo/Gel could promote the regular collagen deposition, angiogenesis, and hair follicle mosaicism regeneration. These results proved that the hydrogel dressing with ADMSCs-derived exosomes can accelerate skin wound healing, which is a strategy for developing wound dressings.
通讯机构：
[Yan, JT ; Sun, Y] W;Wuhan Polytech Univ, Coll Chem & Environm Engn, Wuhan 430023, Peoples R China.
关键词：
Na0.44MnO2;Li2MnO3;nanobelts;molten-salt method;rate performance;cathode material
摘要：
Li2MnO3 nanobelts have been synthesized via the molten salt method that used the Na0.44MnO2 nanobelts as both the manganese source and precursor template in LiNO3-LiCl eutectic molten salt. The electrochemical properties of Li2MnO3 reduced via a low-temperature reduction process as cathode materials for lithium-ion batteries have been measured and compared. Particularly investigated in this work are the effects of the synthesis conditions, such as reaction temperature, molten salt contents, and reaction time on the morphology and particle size of the synthesized Na0.44MnO2 precursor. Through repeated synthesis characterizations of the Na0.44MnO2 precursor, and comparing the electrochemical properties of the reduced Li2MnO3 nanobelts, the optimum conditions for the best electrochemical performance of the reduced Li2MnO3 are determined to be a molten salt reaction temperature of 850 degrees C and a molten salt amount of 25 g. When charge-discharged at 0.1 C (1 C = 200 mAh g(-1)) with a voltage window between 2.0 and 4.8 V, the reduced Li2MnO3 synthesized with reaction temperature of Na0.44MnO2 precursor at 850 degrees C and molten salt amounts of 25 g exhibits the best rate performance and cycling performance. This work develops a new strategy to prepare manganese-based cathode materials with special morphology.
期刊：
Biosensors and Bioelectronics,2023年227:115158 ISSN：0956-5663
通讯作者：
Li, Cheng-Yu(li-chengyu@wust.edu.cn)
作者机构：
[Liu, Da; Li, Cheng-Yu] Wuhan Univ Sci & Technol, Med Coll, Sch Publ Hlth, Hubei Prov Key Lab Occupat Hazard Identificat & Co, Wuhan 430065, Peoples R China.;[Sun, Xiao-Ming] Hubei Univ Med, Biomed Res Inst, Sch Basic Med Sci, Shiyan 442000, Peoples R China.;[Zhu, Lian] Wuhan Polytech Univ, Sch Chem & Environm Engn, Wuhan 430023, Peoples R China.
通讯机构：
[Cheng-Yu Li] H;Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Public Health, Medical College, Wuhan University of Science and Technology, Wuhan, 430065, PR China
摘要：
The thin-walled hollow MoS2 microsphere was synthesized by a facile released online NH3-blowing during the reduction of ammonium tetrathiomolybdate ((NH4)2MoS4) in N-methylpyrrolidone (NMP) solvent by hydrazine hydrate at 80  and investigated electrochemically as sulfur host for lithium sulfur battery. The results show that the as-prepared MoS2 @S electrode delivers an initial specific capacity of as high as 1801 mAh g-1, albeit partly due to the formation of SEI membrane, indicating the modulation of MoS2 on the electrochemical reaction of sulfur when compared with bare sulfur electrode. Moreover, the as-prepared MoS2 @S electrode exhibits ex-cellent cycling stability and good rate capability, corroborating the interaction of MoS2 with lithium polysulfides (LiPSs) due to the severe shuttling effect in lithium sulfur battery, which is further authenticated by cyclic voltammetry, Tafel plot and electrochemical impedance spectroscopy techniques. This is anticipated to be a straightforward strategy for the practical implementation of lithium sulfur battery as an alternative to the state-of -the-art lithium ion battery.
期刊：
Chemical Physics Letters,2023年813:140322 ISSN：0009-2614
通讯作者：
Chen, Licai(chenlc1219@whut.edu.cn)
作者机构：
[Zhang, Tingting] Wuhan Polytech Univ, Sch Chem & Environm Engn, 68 Xuefu South Rd, Wuhan 430023, Hubei, Peoples R China.;[Li, Mingliang; Chen, Licai; Zhao, Yunliang] Wuhan Univ Technol, Sch Resources & Environm Engn, 34 Wenzhi St, Wuhan 430070, Hubei, Peoples R China.;[Bai, Haoyu] Imperial Coll London, Dept Mat, London SW7, England.;[Wang, Wei] Zhengzhou Univ, Sch Chem Engn, Zhengzhou 450001, Henan, Peoples R China.;[Zhao, Yunliang] Wuhan Clayene Technol Co Ltd, 36 Tangxunhu North Rd, Wuhan 430223, Hubei, Peoples R China.
通讯机构：
[Licai Chen; Yunliang Zhao] S;School of Resources and Environmental Engineering, Wuhan University of Technology, 34 Wenzhi Street, Wuhan, Hubei 430070, China<&wdkj&>School of Resources and Environmental Engineering, Wuhan University of Technology, 34 Wenzhi Street, Wuhan, Hubei 430070, China<&wdkj&>Wuhan Clayene Technology Co., Ltd., 36 Tangxunhu North Road, Wuhan, Hubei 430223, China
作者机构：
[Li, Jianfen; Zhu, Longkai; He, Yun; Li, Hui; Wang, Jiaqi] Wuhan Polytech Univ, Sch Chem & Environm Engn, Wuhan 430023, Hubei, Peoples R China.;[Hu, Jue; Zhang, Chengxu] Kunming Univ Sci & Technol, Fac Met & Energy Engn, Engn Lab Adv Battery & Mat Yunnan Prov, Kunming, Peoples R China.;[Zhang, Yizhen] Shandong Univ Sci & Technol, Coll Safety & Environm Engn, Qingdao, Peoples R China.;[Leung, Michael K. H.; Hu, Jue] City Univ Hong Kong, Abil R&D Energy Res Ctr, Sch Energy & Environm, Hong Kong, Peoples R China.;[Leung, Michael K. H.] City Univ Hong Kong, State Key Lab Marine Pollut, Hong Kong, Peoples R China.
通讯机构：
[Jue Hu] T;[Jianfen Li] S;[Michael K.H. Leung] A;The Engineering Laboratory of Advanced Battery and Materials of Yunnan Province, Faculty of Metallurgical and Energy Engineering, Kunming University of Science and Technology, Kunming, PR China<&wdkj&>School of Chemical and Environmental Engineering, Wuhan Polytechnic University, Wuhan, 430023 Hubei, PR China<&wdkj&>Ability R&D Energy Research Centre, School of Energy and Environment, City University of Hong Kong, Hong Kong, China<&wdkj&>State Key Laboratory of Marine Pollution, City University of Hong Kong, Hong Kong, China
摘要：
A dual-photoelectrode PFC system was constructed using an excellent SnO2/BiOBr/MoS2 as a photoanode and copper oxide/copper as a photocathode for the first time. The appropriate interfacial contact and outstanding photoelectrochemical activity of the photoanode can be attributed to SnO2 hole-blocking layer. It is not only employed as a conductive scaffold for BiOBr/MoS2 but also provided less tendency for charge transport loss. In addition, the by-product Bi2S3 acts as a sensitizer due to its broad absorption spectrum (similar to 800 nm) to increase light harvesting. The resulting SnO2/BiOBr/MoS2 photoanode yields the highest photocurrent density at all bias voltages and achieves 4.0 mA cm(-2), which is around eight times higher in comparison with bare BiOBr while it is twice as much as that of the BiOBr/MoS2 photoanode without SnO2 hole reflection layer. This study demonstrates that recombination is significantly inhibited by adding methylene blue (MB) as the hole scavenger, resulting in a high power output efficiency in the dual-photoelectrode PFC system. An ultrahigh power density of 0.045 mW cm(-2) and improved photodegradation efficiency to reach similar to 91 % after 180 min. The excellent power density can therefore be assumed that the enriched strong oxidizing photoexcited holes were used to participate in directly decomposing MB.
摘要：
Hydrogel electrolytes containing a large amount of freezable water tend to freeze at subzero temperatures, which catastrophically reduces their ionic conductivity and thus limits their practical applications. In this work, we propose a new type anti-freezing hydrogel electrolyte based on an additive of zwitterionic proline, which can maintain high ionic conductivities of hydrogel electrolytes at subzero temperatures. The unique zwitterionic structure leads to several interesting characters like strong hydration, strong ionic interactions and low self-associations, which is proved to be the keys for the high performance of hydrogel electrolytes under low temperatures. As a result, the proline hydrogel electrolytes show a high ionic conductivity of 4.2 mS cm(-1) even at -40°C. The activated carbon electrode of supercapacitors based on proline hydrogel electrolytes delivers high specific capacitances of 145.8 (at 0.5 A g(-1)) and 116.1 F g(-1) (at 0.5 A g(-1)) at 25 and -30°C, respectively. Furthermore, the specific capacitance still shows a high retention of 71% after 12,000 charge/discharge cycles at -30°C, confirming the good low-temperature adaptability. Such anti-freezing electrolytes with high ionic conductivity will open up a new avenue for anti-freezing energy storage devices, not limited to supercapacitors.
摘要：
Once nanoparticles enter into the biological milieu, nanoparticle-biomacromolecule complexes, especially the protein corona, swiftly form, which cause obvious effects on the physicochemical properties of both nanoparticles and proteins. Here, the thermodynamic parameters of the interactions between water-soluble GSH-CdSe/ZnS core/shell quantum dots (GSH-QDs) and human serum albumin (HSA) were investigated with the aid of labeling fluorescence of HSA. It was proved that the labeling fluorescence originating from a fluorophore (BDP-CN for instance) could be used to investigate the interactions between QDs and HSA. Gel electrophoresis displayed that the binding ratio between HSA and QDs was similar to 2:1 by direct visualization. Fluorescence resonance energy transfer (FRET) results indicated that the distance between the QDs and the fluorophore BDP-CN in HSA was 7.2 nm, which indicated that the distance from the fluorophore to the surface of the QDs was similar to 4.8 nm. Fluorescence correlation spectroscopy (FCS) results showed that HSA formed a monolayer of a protein corona with a thickness of 5.5 nm. According to the spatial structure of HSA, we could speculate that the binding site of QDs was located at the side edge (not the triangular plane) of HSA with an equilateral triangular prism. The elaboration of the thermodynamic parameters, binding ratio, and interaction orientation will highly improve the fundamental understanding of the formation of protein corona. This work has guiding significance for the exploration of the interactions between proteins and nanomaterials.
摘要：
In this work, the polyvinyl pyrrolidone (PVP) was blended with the material of polyvinylidene fluoride modified by imidazolium ionic liquid (PVDF-IL) and finally a kind of porous PVDF-IL-PVP composite membrane was successfully prepared after membrane casting and ethanol treatment. The porous structure of the membranes was evaluated by SEM in detail and the existence of PVP was also proved by FTIR results. Combining with the porous structure and the addition of PVP, the water uptake and acid uptake of the membranes were improved a lot which greatly promoted the affinity between the electrolytes and the membranes. The properties of the PVDF-IL-PVP membranes were investigated systematically. The modified membranes showed a great increment in ion conductivity. Additionally, the vanadium permeabilities of PVDF-IL-PVP20 and PVDF-IL-PVP30 membranes were also lower than that of Nafion115. At the current density of 100 mA/cm2, the battery assembled with the PVDF-IL-PVP30 membrane exhibited higher Coulombic efficiency (97.82% vs. 97.29%), voltage efficiency (85.17% vs. 82.30%), and energy efficiency (83.31% vs. 80.07%) compared to Nafion115, in conjunction with excellent cycle stability in vanadium redox flow batteries (VRFBs). In conclusion, this work provides a kind of well-performed membrane that has great potential for the application in VRFBs.
摘要：
In this study, for the first time, a novel separation and preconcentration method of direct immersion dual-drop microextraction (DIDDME) was proposed for the species of inorganic chromium (Cr(III) and Cr(VI)) followed by graphite furnace atomic absorption spectrometry detection. The methodology is based on that two organic drops hold on the needle tips of microsyringes were concurrently immersed in a stirred sample solution. Each drop contains a chelating reagent, which can react with a specific species under the same pH value. Therefore, Cr(III) and Cr(VI) can be selectively extracted into different drops. This procedure did not require tedious and complicated pre-oxidation/pre-reduction and centrifugation/filtration operations, which may lead to the risk of sample contamination and analysis errors. Main parameters influencing separation, preconcentration and identification of the target species were investigated. An enrichment factor of 400-fold was obtained for Cr(III) and Cr(VI). Under the optimized conditions, detection limits for this method were 1.1ngL(-1) and 1.4ngL(-1) for Cr(III) and Cr(VI) with relative standard deviations of 5.1 and 6.3%, respectively. This procedure was applied for the separation, preconcentration and determination of Cr(III) and Cr(VI) in environmental water samples and certified reference materials with satisfactory results. Recoveries of spiked experiments ranged from 86.0 to 112%.
通讯机构：
[Liu, Y; Liu, YJ ] T;[Liu, Y ] W;Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China.;Tiangong Univ, State Key Lab Separat Membranes & Membrane Proc, Sch Chem, Tianjin 300387, Peoples R China.;Tiangong Univ, Sch Mat Sci & Engn, Tianjin 300387, Peoples R China.
摘要：
In many types of cancers, pyruvate dehydrogenase kinase (PDK) is abnormally overexpressed and has become a promising target for cancer therapy. However, few highly effective inhibitors of PDK have been reported to date. Herein, we designed and synthesized a series of PDK inhibitors based on dichloroacetate (DCA) and arsenicals. Of the 27 compounds, 1f demonstrated PDK inhibition with high efficiency at a cellular level (IC(50) = 2.0 μM) and an enzyme level (EC(50) = 68 nM), far more effective than that of DCA. In silico, in vitro, and in vivo studies demonstrated that 1f inhibited PDK, shifted the energy metabolism from aerobic glycolysis to oxidative phosphorylation, and induced cell apoptosis. Moreover, new 1f-loaded nanoparticles were developed, and the administration of high-drug-loading nanoparticles (0.15 mg/kg) caused up to 90% tumor shrinkage without any apparent toxicity. Hence, this study provided a novel metabolic therapy for cancer treatment.
通讯机构：
[Akira Nakayama] S;School of Power and Energy, Northwestern Polytechnical University, Xi'an, Shaanxi 710072, China<&wdkj&>Faculty of Engineering, Shizuoka University, Hamamatsu, Shizuoka 432-8561, Japan
摘要：
The Graetz problem in a transpiration-cooled channel was analytically attacked so as to explore the developing temperature field due to a sudden change in wall temperature of the channel subject to an arbitrary distribution of the local mass flux over the porous wall. Analytical expressions for the developments of the thermal boundary layer thickness, wall temperature, and Nusselt number were obtained for the thermal entrance region, assuming hydrodynamically forced convective flow in a channel with a locally variable blowing mass flux. When the blowing mass flux is kept constant over the wall surface, the cooling by the coolant is less effective near the entrance, thus, exposing to danger of thermal damage. This study reveals that the blowing mass flux graded inversely proportional to one-third power of the axial distance is quite effective to keep the wall temperature uniform. Numerical calculations based on finite volume method were also carried out to verify the analysis. The findings from this study can be applied to possible thermal managements of heat generating stacks such as in EV batteries and PEMFC, in which temperature uniformity is essential for product longevity.
摘要：
PurposeThe purpose of this study is to investigate the reliability of flex-on-board (FOB) interconnection connected with an anisotropic conductive paste (ACP), which is prepared by dispersing nickel balls in the epoxy-curing system. Design/methodology/approachDifferential scanning calorimetry was used to evaluate the curing characteristics of the paste. And the contact resistances of bonding joints and 90o peel adhesion were tested before and after high temperature and high humidity test (85 degrees C, 85% humidity), thermal cycling (-45 degrees C similar to 125 degrees C, 30min/cycle) and pressure cooker test (PCT, 121 degrees C, 100% humidity 2 atm) to evaluate the flex on board (FOB) interconnection reliability. FindingsIt is found that FOB test vehicles have been successfully bonded by using ACP for the first time. And the ACP bonding joint of FOB has good reliability and can meet the requirements of FOB interconnection. Compared with conventional anisotropic conductive film (ACF), this ACP interconnection provides higher adhesion strength, higher joint current carrying capability and higher reliability performance and lower cost for FOB interconnection. Originality/valueACP is applied in the interconnection of FOB. It has the higher reliability performance and lower cost for than the conventional ACF.
摘要：
Catalytic oxidation technology is currently considered as a feasible approach to degrade and mineralize volatile organic compounds (VOCs). However, it is still challenging to realize efficient removal of VOCs through catalytic oxidation at room temperature. In our study, a novel flow-through electrocatalytic reactor was designed, composed of porous solid-electrolyte, gas-permeable titanium sub-oxides/titanium-foam (TiSO/Ti-foam) as anode and platinum coated titanium foam (Pt/Ti-foam) as cathode. This device could oxidize nearly 100% of benzene (10 ppm) to carbon dioxide at a current density of 1.2 mA/cm2 under room temperature. More importantly, the device maintained excellent stability over 1000 h. Mechanism of benzene mineralization was discussed. Hydroxyl radicals generated on the TiSO/Ti-foam anode played a crucial role in the oxidation of benzene. This study provides a promising prototype of the electrochemical air purifier, and may find its application in domestic and industrial air pollution control.
通讯机构：
[Feng-Lei Jiang] S;Sauvage Center for Molecular Sciences, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, P. R. China
期刊：
Journal of Molecular Liquids,2023年388:122773 ISSN：0167-7322
通讯作者：
Zhang, LJ;Zhang, Lingjie;Zhao, YL
作者机构：
[Zhang, Lingjie; Song, Guangsen; Zhao, Yinxing; Zhang, Tingting; Fan, Guozhi; Zhang, LJ] Wuhan Polytech Univ, Sch Chem & Environm Engn, Wuhan 430023, Hubei, Peoples R China.;[Zhang, Lingjie; Zhang, LJ; Zhao, YL; Zhao, Yunliang; Zhang, Qiwu] Wuhan Univ Technol, Sch Resources & Environm Engn, Wenzhi St 34, Wuhan 430070, Hubei, Peoples R China.;[Zhang, Lingjie; Zhang, LJ] Univ Autonoma San Luis Potosi, Fac Ciencias, Av Parque Chapultepec 1570, San Luis Potosi 78210, San Luis Potosi, Mexico.;[Zhao, YL; Zhao, Yunliang] Wuhan Clayene Technol Co Ltd, Tangxunhu North Rd 36, Wuhan 430223, Hubei, Peoples R China.
通讯机构：
[Zhang, LJ; Zhao, YL ; Zhang, LJ ] W;Wuhan Polytech Univ, Sch Chem & Environm Engn, Wuhan 430023, Hubei, Peoples R China.;Wuhan Univ Technol, Sch Resources & Environm Engn, Wenzhi St 34, Wuhan 430070, Hubei, Peoples R China.;Univ Autonoma San Luis Potosi, Fac Ciencias, Av Parque Chapultepec 1570, San Luis Potosi 78210, San Luis Potosi, Mexico.;Wuhan Clayene Technol Co Ltd, Tangxunhu North Rd 36, Wuhan 430223, Hubei, Peoples R China.
关键词：
Para arsanilic acid;Ca-Al-Fe composites;Adsorption;Mechanism;Performance
摘要：
Para arsanilic acid (p-ASA) as the one of the sources of highly toxic and carcinogenic inorganic arsenic is frequently excreted into the aqueous systems, raising serious environmental hazards and human health risks. Thus, it is compelling to develop techniques that can realize high efficiency of p-ASA removal while being cost effective. Here, a ternary composite material Ca-Al-Fe was designed via facile mechanochemistry and lowtemperature calcination on the mixture of inexpensive and readily available Ca(OH)(2), C6H9AlO6 and FeC2O4. The results showed that the resulting Ca-Al-Fe composite was capable of achieving a preferable p-ASA adsorption from water with high adsorption capacity (41.23 mg/g), fast kinetic (30 min), long-term stability and reusability on account of the interfacial synergetic effect between ternary composite components. Furthermore, the mechanism investigation demonstrated that, in the preparation stage, CO2 was liberated by the decomposition of FeC2O4, leading to a favorable porous structure and the formation of CaCO3. In the adsorption stage, the hydrolysis of generated CaCO3 enabled the continuous release of OH-, which induced in situ formation of high reactive Fe and Al hydroxides by Al3+ and Fe3+ to adsorb p-ASA by hydrogen bond and coordination interactions. The current work provides a new insight and direction for the development of high-performance metal composite materials.
