A-type procyanidins is rich in litchi pericarp. This study evaluated the prevention and anti diabetic effect of A-type oligomeric procyanidins (A-OPC). The results showed A-OPC was more effective than B-type oligomeric procyanidins (B-OPC) of lotus seedpod. AMP activated protein ldnase (AMPK) was activated in liver and skeletal muscle. The protein levels of glucokinase (GK), glucose transporter type 2 (GLUT2, in liver), glucose transporter type 4 (GLUT4, in skeletal muscle) and insulin receptor a (INSR) improved significantly with treatment of A-OPC or B-OPC (p < 0.05). Furthermore, the glycol...