作者机构：
[Tse, Lap Ah; Li, Wenzhen] Chinese Univ Hong Kong, Jockey Club Sch Publ Hlth & Primary Care, Hong Kong, Peoples R China.;[Tse, Lap Ah; Li, Wenzhen] Chinese Univ Hong Kong, Shenzhen Res Inst, Shenzhen, Peoples R China.;[Zhao, Zhiya] Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Dept Social Med & Hlth Management, Wuhan 430030, Hubei, Peoples R China.;[Chen, Dajie] Wuhan Polytech Univ, Dept Hlth Serv & Management, Wuhan 430030, Hubei, Peoples R China.;[Kwan, Mei-Po] Chinese Univ Hong Kong, Dept Geog & Resource Management, Hong Kong, Peoples R China.
通讯机构：
[Tse, LA ; Li, WZ] C;Chinese Univ Hong Kong, Jockey Club Sch Publ Hlth & Primary Care, Hong Kong, Peoples R China.;Chinese Univ Hong Kong, Shenzhen Res Inst, Shenzhen, Peoples R China.;Chinese Univ Hong Kong, Inst Space & Earth Informat Sci, Hong Kong, Peoples R China.
关键词：
Anxiety;Depression;Health locus of control;Health risk behavior
摘要：
We aimed to assess the association of health locus of control with anxiety and depression, and explore the mediating effects of health risk behaviors. A multi-stage cluster random sampling method was used among Chinese college students. Logistic regression models were used to explore the associations of health locus of control with anxiety and depression. Structural equation models were used to explore the mediation roles of health risk behaviors in the associations of health locus of control with anxiety and depression. A total of 3,951 college students were included in this study. Internality was associated with lower prevalence of depression (OR = 0.94, 95% CI, 0.91-0.97), powerful others externality was also associated with lower prevalence of anxiety and depression (0.92, 0.88-0.96; 0.93, 0.89-0.96), while chance externality was associated with higher risk of anxiety and depression (1.13, 1.08-1.18; 1.24, 1.20-1.28). The mediated proportion of health risk behaviors in associations of internality, powerful others externality, chance externality with anxiety was 7.55%, 2.37% and 2.18%, respectively. The mediated proportion of health risk behaviors in associations of powerful others externality, chance externality with depression was 10.48% and 2.14%, respectively. Health locus of control is associated with anxiety and depression that are mediated by health risk behaviors.
期刊：
Separation and Purification Technology,2025年354:128695 ISSN：1383-5866
通讯作者：
Xiaofeng Wu<&wdkj&>Kangle Lv
作者机构：
[Yu, Mengxue; Chang, Shixin; Ma, Liang; Ding, Yaobin; Zhang, Xue; Lv, Kangle] Key Laboratory of Catalysis and Materials Science of the State Ethnic Affairs Commission & Ministry of Education, College of Resources and Environment, South−Central Minzu University, Wuhan 430074, China;[Yan, Juntao] School of Chemical and Environmental Engineering, Wuhan Polytechnic University, Wuhan 430023, China;[Sónia A.C. Carabineiro] LAQV-REQUIMTE, Department of Chemistry, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal;[Wu, Xiaofeng] Key Laboratory of Catalysis and Materials Science of the State Ethnic Affairs Commission & Ministry of Education, College of Resources and Environment, South−Central Minzu University, Wuhan 430074, China<&wdkj&>School of Chemical and Environmental Engineering, Wuhan Polytechnic University, Wuhan 430023, China
通讯机构：
[Xiaofeng Wu; Kangle Lv] K;Key Laboratory of Catalysis and Materials Science of the State Ethnic Affairs Commission & Ministry of Education, College of Resources and Environment, South−Central Minzu University, Wuhan 430074, China<&wdkj&>School of Chemical and Environmental Engineering, Wuhan Polytechnic University, Wuhan 430023, China<&wdkj&>Key Laboratory of Catalysis and Materials Science of the State Ethnic Affairs Commission & Ministry of Education, College of Resources and Environment, South−Central Minzu University, Wuhan 430074, China
摘要：
The nitrogen oxide emissions originating from combustion pose significant risks to the environment. Photocatalysis is considered an efficient and environmentally friendly strategy to alleviate this problem. Graphitic carbon nitride (g-C3N4) is regarded as one of the most promising organic photocatalytic materials for environmental purification. However, its small specific surface area, weak adsorption and high recombination rate of charge carriers result in low intrinsic photocatalytic activity. To overcome these obstacles, a hydrothermal treatment of dicyandiamide-derived g-C3N4 (DCN) at different temperatures (140–200 °C) was employed to enhance the photocatalytic activity for NO oxidation. The experimental results demonstrated a significant improvement in the photocatalytic oxidation removal rate of NO after a hydrothermal treatment. The optimal photocatalyst, DCN-180, treated at 180 °C, demonstrated the highest NO removal efficiency (65.0 %), which is twice the value of pristine DCN (32.5 %). Additionally, the formation of the toxic intermediate NO2 was effectively suppressed during the reaction. Photoelectrochemical tests revealed that DCN-180 exhibited higher photocurrent density and smaller impedance radius compared to the untreated g-C3N4 sample. Moreover, density functional theory (DFT) calculations confirmed that the DCN-180 sample showed a stronger ability to adsorb O2 and NO. The enhanced photocatalytic NO oxidation performance of DCN-180 has been primarily attributed to its enlarged specific surface area (from 10.7 to 35.5 m2 g−1), local polarization effect, reduced interfacial charge transfer resistance, and improved adsorption abilities for NO and O2 molecules. This study provides valuable insights for designing and preparing highly efficient g-C3N4 based photocatalysts through surface modification for photocatalytic NO purification.
The nitrogen oxide emissions originating from combustion pose significant risks to the environment. Photocatalysis is considered an efficient and environmentally friendly strategy to alleviate this problem. Graphitic carbon nitride (g-C3N4) is regarded as one of the most promising organic photocatalytic materials for environmental purification. However, its small specific surface area, weak adsorption and high recombination rate of charge carriers result in low intrinsic photocatalytic activity. To overcome these obstacles, a hydrothermal treatment of dicyandiamide-derived g-C3N4 (DCN) at different temperatures (140–200 °C) was employed to enhance the photocatalytic activity for NO oxidation. The experimental results demonstrated a significant improvement in the photocatalytic oxidation removal rate of NO after a hydrothermal treatment. The optimal photocatalyst, DCN-180, treated at 180 °C, demonstrated the highest NO removal efficiency (65.0 %), which is twice the value of pristine DCN (32.5 %). Additionally, the formation of the toxic intermediate NO2 was effectively suppressed during the reaction. Photoelectrochemical tests revealed that DCN-180 exhibited higher photocurrent density and smaller impedance radius compared to the untreated g-C3N4 sample. Moreover, density functional theory (DFT) calculations confirmed that the DCN-180 sample showed a stronger ability to adsorb O2 and NO. The enhanced photocatalytic NO oxidation performance of DCN-180 has been primarily attributed to its enlarged specific surface area (from 10.7 to 35.5 m2 g−1), local polarization effect, reduced interfacial charge transfer resistance, and improved adsorption abilities for NO and O2 molecules. This study provides valuable insights for designing and preparing highly efficient g-C3N4 based photocatalysts through surface modification for photocatalytic NO purification.
作者机构：
Sinagri YingTai Bio-peptide Co., Ltd., Linzhou 456550, China;School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan 420200, China;Key Laboratory of Feed Antibiotics Replacement Technology, Ministry of Agriculture and Rural Affairs, Linzhou 456550, China;[Zhihao Li] Hubei Key Laboratory of Animal Nutrition and Feed Science, Engineering Research Center of Feed Protein Resources on Agricultural By-Products, Ministry of Education, Wuhan Polytechnic University, Wuhan 430023, China;Author to whom correspondence should be addressed.
通讯机构：
[Yujiao Lai] H;Hubei Key Laboratory of Animal Nutrition and Feed Science, Engineering Research Center of Feed Protein Resources on Agricultural By-Products, Ministry of Education, Wuhan Polytechnic University, Wuhan 430023, China<&wdkj&>Author to whom correspondence should be addressed.
摘要：
Sublancin, an S-linked antimicrobial (glycol) peptide produced by Bacillus subtilis, has emerged as a novel and promising veterinary drug due to its unique antibacterial mechanism, low risk of resistance, and properties that modulate the immune system, reduce inflammation, and promote gut health. This study comprehensively assessed the subchronic (90-day) and chronic (180-day) toxicity of Sprague–Dawley (SD) rats, following the guidelines issued by the Ministry of Agriculture of China. Rats were orally administered sublancin at doses of 2000, 10,000, or 50,000 mg/kg feed, representing 1666–5000 times the efficacious dose (1.0–1.2 mg/kg) reported in mice via the same administration route. Throughout this study, a wide range of physiological and behavioral parameters were monitored to access the toxicity of sublancin, including appetite, water intake, body weight gain, and organ weights. Hematological and biochemical analyses, as well as histopathological examinations of the major organs, were conducted at the end of each study period. The results indicated no adverse effects on any measured parameters at any dose level, with no significant differences observed between the sublancin-treated groups and the control group (p > 0.05). Notably, even the highest dose of 50,000 mg/kg did not induce growth inhibition or physiological dysfunction. A histopathological examination also revealed no tissue abnormalities in the major organs. The no-observed-effect level (NOEL) was determined to be 50,000 mg/kg for both study periods. These results demonstrate the long-term safety of sublancin in Sprague–Dawley rats, with no adverse effects during 180 days of oral administration at doses 1666–5000-fold the documented antimicrobially effective and immune-enhancing doses.
摘要：
Lignin is the only natural polymer compound containing a benzene ring on earth, and its conversion to monophenolic compounds is attracting more attention. Cu-dopped CuCo 2 O 4 is synthesized and further used to catalyze the oxidative conversion of lignin to monophenolic compounds. It is found that the conversion of lignin is affected by the molar ratio of Cu to Co, the amounts of catalyst and H 2 O 2 , reaction temperature and time, and CuCo 2 O 4 exhibits excellent catalytic performance. Under the optimized reaction conditions, the total yield of monophenolic compounds reaches 21.7%. CuCo 2 O 4 also possesses good recyclable performance, and the total yield of monophenolic compounds slightly drops to 17.6% after four cycles. A plausible mechanism for the conversion of lignin to monophenolic compounds is proposed. During the depolymerization of lignin, C O and C C bonds are broken to form monophenols. This work provides an effective catalyst for the conversion of lignin to monophenol and expands the way of high-value utilization of biomass.
期刊：
Current Microbiology,2025年82(4):183 ISSN：0343-8651
通讯作者：
Geng, YM
作者机构：
[Wei, Hehong; Yao, Ying; Geng, Yamin; Ding, Bingqing] Hebei Univ Engn, Coll Energy & Environm Engn, Handan 056038, Peoples R China.;[Gao, Na] Anhui Acad Agr Sci, Fisheries Res Inst, Key Lab Freshwater Aquaculture & Enhancement Anhui, Hefei 230031, Peoples R China.;[Liu, Yaqi] Chinese Acad Sci, Inst Hydrobiol, Key Lab Breeding Biotechnol & Sustainable Aquacult, Wuhan 430072, Peoples R China.;[Liu, Yaqi] Univ Chinese Acad Sci, Beijing 100049, Peoples R China.;[Dai, Jingcheng; Sun, Yangyang] Wuhan Polytech Univ, Sch Life Sci & Technol, Wuhan 430023, Peoples R China.
通讯机构：
[Geng, YM ] H;Hebei Univ Engn, Coll Energy & Environm Engn, Handan 056038, Peoples R China.
摘要：
A novel bacterial strain, designated Dechloromonas aquae ZY10(T), was isolated from the aquaculture water of grass carp. The colonies exhibited diameters ranging from approximately 1 to 3mm and were characterized by a creamy-white coloration, circular shape, smooth texture, translucency, and a convex profile. The cells were facultatively anaerobic and motile, utilizing a single polar flagellum for movement. They were rod-shaped, reproduced through binary fission, and were identified as Gram-negative, oxidase-negative, and catalase-positive. Optimal growth was observed between 37 and 40°C, within a pH range of 7.0-9.0, and at a NaCl concentration of 0% (w/v). The respiratory quinone was ubiquinone-8 (97.6%) and ubiquinone-7 (2.4%), and the major polar lipids were phosphatidylethanolamine (PE), aminophospholipid (APL), diphosphatidylglycerol (DPG), and phosphatidylglycerol (PG). Phylogenetic analysis based on 16S rRNA gene sequences suggested that ZY10(T) formed a lineage within the genus Dechloromonas and showed the highest 16S rRNA gene sequence similarity to "D. hankyongensis" XY25(T) (96.5%), followed by D. denitrificans ED1(T) (96.4%), D. hortensis MA-1(T) (96.1%) and D. agitata CKB(T) (96.0%) and Azonexus. caeni Slo-05(T) (95.5%). The predominant fatty acids of ZY10(T) were summed feature 3 (comprising C(16:1) ω6c and/or C(16:1) ω7c) and C(16:0). The whole genome of ZY10(T) was 3,568,927bp in size, including 3,275 protein-coding genes, 72 tRNA genes, and 15 rRNA genes, and the genomic DNA G + C content was 62.0mol%. The orthologous average nucleotide identity, average amino acid identity, and digital DNA-DNA hybridization values between ZY10(T) and other species within the family Azonexaceae were 78.0-81.5%, 71.8-73.9%, and 20.3-23.0%, respectively. Therefore, based on phenotypic, chemotaxonomic, and phylogenetic analyses, the isolated ZY10(T) (= MCCC 1K08699(T) = KCTC 72749(T)) is proposed as type strain of the novel species Dechloromonas aquae sp. nov.
作者机构：
[Lin Jia; Wenjun Jia; Wuao Tang] School of Navigation, Wuhan University of Technology, Wuhan 430063, China;Hubei Key Laboratory of Inland Shipping Technology, Wuhan 430063, China;School of Mathematics and Computer Science, Wuhan Polytechnic University, Wuhan 430048, China;[Lichuan Wu] Department of Earth Sciences, Uppsala University, Uppsala 75236, Sweden;[Chunhui Zhou] School of Navigation, Wuhan University of Technology, Wuhan 430063, China<&wdkj&>Hubei Key Laboratory of Inland Shipping Technology, Wuhan 430063, China
通讯机构：
[Hongxun Huang] H;Hubei Key Laboratory of Inland Shipping Technology, Wuhan 430063, China<&wdkj&>School of Mathematics and Computer Science, Wuhan Polytechnic University, Wuhan 430048, China
关键词：
To visualize the research hotspots and development direction of green ships in the fields of technology;operation and policy measures;this subsection applies the Co-occurrence Analysis of VOSviewer to generate a visual map. VOSviewer software's clustering algorithm is primarily based on the correlation intensity algorithm;which selects high-frequency keywords in the text for clustering analysis;and reflects the research theme of the discipline through high-frequency keywords. The analysis
摘要：
With the increased global focus on environmental protection, green ships have emerged as the cornerstone to the maritime industry's long-term development. Based on the knowledge graph method, this paper uses bibliometric analysis to examine the research progress of green ships in a multidimensional perspective. Firstly, sort out the definition and connotation of green ships, and clarify their greening requirements in the whole life cycle. Bibliometric analysis of relevant literature using the bibliometrix package; secondly, combined with the virtual analysis method-VOSviewer software, it explores the current research status of green ships from the multi-dimensional perspectives of technical, operational and policy. The results indicate that the hot spots in technical measures are “green energy”, “ship optimization” and “waste heat recovery”; the hot spots in operational measures are “speed optimization” and “liner shipping”; and the hot spots in policy measures are “market mechanism” and “international regulations”.
With the increased global focus on environmental protection, green ships have emerged as the cornerstone to the maritime industry's long-term development. Based on the knowledge graph method, this paper uses bibliometric analysis to examine the research progress of green ships in a multidimensional perspective. Firstly, sort out the definition and connotation of green ships, and clarify their greening requirements in the whole life cycle. Bibliometric analysis of relevant literature using the bibliometrix package; secondly, combined with the virtual analysis method-VOSviewer software, it explores the current research status of green ships from the multi-dimensional perspectives of technical, operational and policy. The results indicate that the hot spots in technical measures are “green energy”, “ship optimization” and “waste heat recovery”; the hot spots in operational measures are “speed optimization” and “liner shipping”; and the hot spots in policy measures are “market mechanism” and “international regulations”.
作者机构：
[Michael Schmitt] Institute of Physical Chemistry (IPC) and Abbe Center of Photonics (ACP), Friedrich Schiller University Jena, Member of the Leibniz Centre for Photonics in Infection Research (LPI), Jena, Germany;[Rustam Guliev] Leibniz Institute of Photonic Technology, Member of Leibniz Health Technologies, Member of the Leibniz Centre for Photonics in Infection Research (LPI), Jena, Germany;[Jonas Ballmaier; Orlando Guntinas-Lichius] Department of Otorhinolaryngology-Head and Neck Surgery, Jena University Hospital, Jena, Germany;[Chen Liu] School of Food Science and Engineering, Wuhan Polytechnic University, Wuhan, China;[Edoardo Farnesi; Juergen Popp; Dana Cialla-May] Institute of Physical Chemistry (IPC) and Abbe Center of Photonics (ACP), Friedrich Schiller University Jena, Member of the Leibniz Centre for Photonics in Infection Research (LPI), Jena, Germany<&wdkj&>Leibniz Institute of Photonic Technology, Member of Leibniz Health Technologies, Member of the Leibniz Centre for Photonics in Infection Research (LPI), Jena, Germany
通讯机构：
[Dana Cialla-May] I;Institute of Physical Chemistry (IPC) and Abbe Center of Photonics (ACP), Friedrich Schiller University Jena, Member of the Leibniz Centre for Photonics in Infection Research (LPI), Jena, Germany<&wdkj&>Leibniz Institute of Photonic Technology, Member of Leibniz Health Technologies, Member of the Leibniz Centre for Photonics in Infection Research (LPI), Jena, Germany
摘要：
Early detection of head and neck cancer (HNC) is critical for improving prognosis and survival rates. Many cases are diagnosed at advanced stages due to subtle initial symptoms and the complexity of the head and neck anatomy, which complicates clinical examination and biopsy procedures. Therefore, there is an urgent need for non-invasive, reliable, and rapid diagnostic methods suitable for point-of-care (POC) settings. In this study, we applied surface-enhanced Raman spectroscopy (SERS) to develop a rapid screening method for HNC diagnosis using cerumen as the medium. The study aimed to utilize a SERS-based machine learning (ML) approach to distinguish between cerumen samples from healthy individuals and those with HNC. Principal Component Analysis and Linear Discriminant Analysis (PCA-LDA) were performed to analyze and differentiate the cerumen samples. By comparing the SERS spectra of healthy donors with those of HNC patients, we identified SERS spectral features associated with the presence of tumors. The PCA-LDA method successfully classified healthy and HNC cerumen samples with 87.2% accuracy, 87.3% specificity, 87% sensitivity, and a 90% area under the receiver operating characteristic (ROC AUC) curve. This cerumen-SERS-ML workflow proved effective for the rapid identification and evaluation of HNC, offering a promising tool for disease diagnosis.
摘要：
In real-world food safety incidents, hazards are often diverse and coexist simultaneously. Mature single-target detection technologies, while effective, are insufficient for comprehensively evaluating the overall quality and safety of food. As a result, multi-target detection, which enables a more comprehensive assessment of multiple hazards in food, has emerged as a prominent research focus. Nanomaterials have gained significant attention in sensing technologies due to their unique advantages, such as high sensitivity and potential for point-of-care detection. Furthermore, nanomaterials hold great promise for multi-target detection technologies because of their versatile properties, including fluorescence and other characteristics that make them suitable for developing a wide range of detection methods. On the basis of systematically summarizing the research achievements of multi-targets sensing in recent five years, this paper categorizes multi-targets sensing nanoprobes construction strategies into five types according to recognition/interaction relationships between the sensing units and targets. In addition, this review also elaborates some practical cases to further explain the design strategy, detection process and detection system of multi-targets sensing nanoprobes, which provides a novel and directional guidance for food detection and food industry management. Finally, according to the shortcomings of current multi-targets sensing nanoprobes, the prospect and challenges of multi-targets sensing nanoprobes are given.
In real-world food safety incidents, hazards are often diverse and coexist simultaneously. Mature single-target detection technologies, while effective, are insufficient for comprehensively evaluating the overall quality and safety of food. As a result, multi-target detection, which enables a more comprehensive assessment of multiple hazards in food, has emerged as a prominent research focus. Nanomaterials have gained significant attention in sensing technologies due to their unique advantages, such as high sensitivity and potential for point-of-care detection. Furthermore, nanomaterials hold great promise for multi-target detection technologies because of their versatile properties, including fluorescence and other characteristics that make them suitable for developing a wide range of detection methods. On the basis of systematically summarizing the research achievements of multi-targets sensing in recent five years, this paper categorizes multi-targets sensing nanoprobes construction strategies into five types according to recognition/interaction relationships between the sensing units and targets. In addition, this review also elaborates some practical cases to further explain the design strategy, detection process and detection system of multi-targets sensing nanoprobes, which provides a novel and directional guidance for food detection and food industry management. Finally, according to the shortcomings of current multi-targets sensing nanoprobes, the prospect and challenges of multi-targets sensing nanoprobes are given.
摘要：
Holocellulose laurate (HC-L) was prepared by the esterification of holocellulose with lauric acid, and then was further melt-blended with poly(butylene adipate-co-terephthalate) (PBAT) and polylactic acid (PLA) to obtain a biodegradable HC-L/PBAT/PLA composite. Compared with those of the PBAT/PLA matrix, the comprehensive properties, including the thermal properties, water stability, gas barrier properties and degradation properties of HC-L/PBAT/PLA with 5 wt% HC-L were improved. The elongation at break and 90-d biodegradation rates increased by 64% and 11.0%, respectively. The water absorption capacity, water vapor transmission and oxygen permeability decreased by 60%, 18.6%, and 33.2%, respectively, and the water contact angle increased from 91.9 degrees to 112 degrees. The elongation at break, thermal stability, water stability and gas barrier properties of HC-L/PBAT/PLA were superior to those of a commercial bio-based pallet. The results showed that modified holocellulose can be used as a filler in biodegradable composites, expanding the utilization of lignocellulosic resources in the packaging field.
摘要：
Chitosan (CTS) exhibits notable moisturizing and film-forming capabilities, whereas nano selenium (SeNPs) demonstrates antioxidant and antibacterial properties. In the present study, a CTS/Se film-forming agent was prepared by dissolving CTS, glycerol, and SeNPs in 1% (v/v) glacial acetic acid through heating and ultrasonic treatment. The results revealed that SeNPs fused with CTS via intermolecular forces, thereby enhancing the tensile strength of the CTS film. The water contact angle of the CTS film increased with an increase in SeNPs concentration. The thermal stability and water retention properties of CTS/Se were superior than CTS. In a storage experiment, the content of soluble solids in tomatoes coated with CTS/Se was higher than that in tomatoes coated with CTS and the control. The CTS/Se coating inhibited gas exchange both inside and outside the film, leading to increased activities of antioxidant enzymes. This reduced the oxidation of vitamin C in the tomatoes and decreased the content of malondialdehyde. The CTS/Se film inhibited the growth of bacteria on the tomato surface and mitigated the decline of aldehyde, alcohol and ketone aroma compounds. Consequently, the CTS/Se coating alleviated the softening, aging and rotting of tomatoes. Feeding experiments conducted on mice verified the food safety of the CTS/Se.
Chitosan (CTS) exhibits notable moisturizing and film-forming capabilities, whereas nano selenium (SeNPs) demonstrates antioxidant and antibacterial properties. In the present study, a CTS/Se film-forming agent was prepared by dissolving CTS, glycerol, and SeNPs in 1% (v/v) glacial acetic acid through heating and ultrasonic treatment. The results revealed that SeNPs fused with CTS via intermolecular forces, thereby enhancing the tensile strength of the CTS film. The water contact angle of the CTS film increased with an increase in SeNPs concentration. The thermal stability and water retention properties of CTS/Se were superior than CTS. In a storage experiment, the content of soluble solids in tomatoes coated with CTS/Se was higher than that in tomatoes coated with CTS and the control. The CTS/Se coating inhibited gas exchange both inside and outside the film, leading to increased activities of antioxidant enzymes. This reduced the oxidation of vitamin C in the tomatoes and decreased the content of malondialdehyde. The CTS/Se film inhibited the growth of bacteria on the tomato surface and mitigated the decline of aldehyde, alcohol and ketone aroma compounds. Consequently, the CTS/Se coating alleviated the softening, aging and rotting of tomatoes. Feeding experiments conducted on mice verified the food safety of the CTS/Se.
作者机构：
[Xie, Min; Lai, Yan; Fei, Dan; Zhou, Yaomin; Zhou, YM; Guang, Yelan] Jiangxi Acad Agr Sci, Inst Qual Safety & Stand Agr Prod, Key Lab Agroprod Qual & Safety Jiangxi Prov, Nanchang 330200, Jiangxi, Peoples R China.;[Xu, Jun] Jiangxi Acad Agr Sci, Inst Anim Husb & Vet Med, Nanchang 330200, Jiangxi, Peoples R China.;[Wu, Na] Jiangxi Agr Univ, Coll Food Sci & Technol, Nanchang 330045, Jiangxi, Peoples R China.;[Cai, Jie] Wuhan Polytech Univ, Sch Modern Ind Selenium Sci & Engn, Wuhan 430023, Hubei, Peoples R China.
通讯机构：
[Zhou, YM ] J;Jiangxi Acad Agr Sci, Inst Qual Safety & Stand Agr Prod, Key Lab Agroprod Qual & Safety Jiangxi Prov, Nanchang 330200, Jiangxi, Peoples R China.
关键词：
Egg quality;Volatile organic compounds;Chemometric analysis;Odor activity value
摘要：
This study analyzed the egg quality of two commercial layers and two local breeds and detected volatile organic compounds (VOCs) using headspace solid-phase microextraction (HS-SPME-GC-MS) coupled with principal components analysis (PCA) and partial least squares discriminant analysis (PLS-DA). A total of 70 VOCs were identified in four types of eggs, mainly including aldehydes, alcohols, ketones, and esters. Chemometric and odor active value (OAV) analysis indicated that cis-3-hexen-1-ol, nonanal, n-decanal, benzaldehyde, and geranial were the main contributing components of flavor in eggs and can also serve as potential marker to distinguish different types of eggs. Both native eggs and commercial eggs have plentiful VOCs. This study contributed to a better understanding of the differences between commercial eggs and native eggs, laying a foundation for the development and utilization of native eggs.
摘要：
The potential health effects of exposure to rare earth elements (REEs) remain largely unexplored. This prospective cohort study aimed to elucidate the association between early pregnancy REE exposure and maternal thyroid function, as well as neonatal birth outcomes, in a cohort of pregnant women in Beijing, China. Additionally, the study explored the mediating role of thyroid homeostasis in the effects of REE exposure. Serum concentrations of fifteen REEs, along with Free Thyroxine (FT4), Thyroid Stimulating Hormone (TSH), and Thyroid Peroxidase Antibodies (TPOAb), were measured in 195 pregnant women. Multivariable linear regression analyses identified significant correlations between REE exposure and disruptions in maternal thyroid homeostasis. Specifically, Praseodymium (Pr) and Lutetium (Lu) were positively associated with FT4 levels, while Gadolinium (Gd) showed a positive correlation with TSH levels. Conversely, Thulium (Tm) was negatively associated with FT4 levels, and Yttrium (Y) was negatively correlated with TSH levels, indicating distinct interactions of specific REEs with thyroid regulation. Notably, Lu remained positively correlated with FT4 levels (β = 1.39, 95% CI = 0.55, 2.22) after adjusting for multiple comparisons. Regarding neonatal birth outcomes, Dysprosium (Dy) was found to be negatively associated with infant birth weight (β = −0.09, 95% CI = −0.170, −0.002). Furthermore, gender-specific analyses revealed significant associations between REE exposure and TPOAb levels among female neonates. Mediation analyses indicated that TSH significantly mediated the relationships between Terbium (Tb) and Y exposure and neonatal birth outcomes. The study suggests that REEs may disrupt endocrine function, particularly thyroid hormones, which could adversely affect neonatal growth, highlighting the need for further research on their impact in vulnerable populations.
The potential health effects of exposure to rare earth elements (REEs) remain largely unexplored. This prospective cohort study aimed to elucidate the association between early pregnancy REE exposure and maternal thyroid function, as well as neonatal birth outcomes, in a cohort of pregnant women in Beijing, China. Additionally, the study explored the mediating role of thyroid homeostasis in the effects of REE exposure. Serum concentrations of fifteen REEs, along with Free Thyroxine (FT4), Thyroid Stimulating Hormone (TSH), and Thyroid Peroxidase Antibodies (TPOAb), were measured in 195 pregnant women. Multivariable linear regression analyses identified significant correlations between REE exposure and disruptions in maternal thyroid homeostasis. Specifically, Praseodymium (Pr) and Lutetium (Lu) were positively associated with FT4 levels, while Gadolinium (Gd) showed a positive correlation with TSH levels. Conversely, Thulium (Tm) was negatively associated with FT4 levels, and Yttrium (Y) was negatively correlated with TSH levels, indicating distinct interactions of specific REEs with thyroid regulation. Notably, Lu remained positively correlated with FT4 levels (β = 1.39, 95% CI = 0.55, 2.22) after adjusting for multiple comparisons.
Regarding neonatal birth outcomes, Dysprosium (Dy) was found to be negatively associated with infant birth weight (β = −0.09, 95% CI = −0.170, −0.002). Furthermore, gender-specific analyses revealed significant associations between REE exposure and TPOAb levels among female neonates. Mediation analyses indicated that TSH significantly mediated the relationships between Terbium (Tb) and Y exposure and neonatal birth outcomes. The study suggests that REEs may disrupt endocrine function, particularly thyroid hormones, which could adversely affect neonatal growth, highlighting the need for further research on their impact in vulnerable populations.
摘要：
Some probiotic films have not shown satisfactory antibacterial performance, which limits their application in food. The purpose of this study is to improve the antibacterial activity of probiotic film by using probiotics to ferment the film solution, and to solve the problem of weak antibacterial performance of probiotic film. In this study, the solution composed of gum arabic/whey protein isolate/isomalt/glycerol was firstly fermented by Lactobacillus rhamnosus (L. rhamnosus) HN001, and then prepared into probiotic fermented films. The effect of probiotic fermentation on the films properties was systematically evaluated in this study. These results demonstrated that probiotic fermentation enhanced the mechanical strength, water barrier properties, thermal stability, and antioxidant activity of the films. According to the scanning electron microscopy (SEM), the probiotic-fermented films exhibited a more compact and coherent structure. Characterization of the films revealed that probiotic fermentation improved the compatibility between the film components and altered the conformation of whey protein. Compared to the non-fermented probiotic films, the probiotic-fermented films exhibited an 11% increase in the inhibition rate against Staphylococcus aureus and a 21% increase in the inhibition rate against Salmonella. The probiotic-fermented films successfully delayed the spoilage of fresh pork stored at 4 °C, effectively inhibiting microbial growth and reproduction, demonstrating a more effective preservation effect than the non-fermented probiotic films. This study provides an effective and convenient method for improving the antibacterial properties and preservation effect of probiotic films.
Some probiotic films have not shown satisfactory antibacterial performance, which limits their application in food. The purpose of this study is to improve the antibacterial activity of probiotic film by using probiotics to ferment the film solution, and to solve the problem of weak antibacterial performance of probiotic film. In this study, the solution composed of gum arabic/whey protein isolate/isomalt/glycerol was firstly fermented by Lactobacillus rhamnosus (L. rhamnosus) HN001, and then prepared into probiotic fermented films. The effect of probiotic fermentation on the films properties was systematically evaluated in this study. These results demonstrated that probiotic fermentation enhanced the mechanical strength, water barrier properties, thermal stability, and antioxidant activity of the films. According to the scanning electron microscopy (SEM), the probiotic-fermented films exhibited a more compact and coherent structure. Characterization of the films revealed that probiotic fermentation improved the compatibility between the film components and altered the conformation of whey protein. Compared to the non-fermented probiotic films, the probiotic-fermented films exhibited an 11% increase in the inhibition rate against Staphylococcus aureus and a 21% increase in the inhibition rate against Salmonella. The probiotic-fermented films successfully delayed the spoilage of fresh pork stored at 4 °C, effectively inhibiting microbial growth and reproduction, demonstrating a more effective preservation effect than the non-fermented probiotic films. This study provides an effective and convenient method for improving the antibacterial properties and preservation effect of probiotic films.
作者机构：
[Mao, Wuxiang; Jin, Shuqi; Zhang, Junqi; Yin, Wenhao; Liu, Yi; Deng, Wenwen; Wang, Xinping; Jiang, Qingyuan] Hubei Univ, Sch Life Sci, State Key Lab Biocatalysis & Enzyme Engn, Wuhan 430042, Hubei, Peoples R China.;[Yin, Wenhao; Liu, Yi] BravoVax Co Ltd, Wuhan 430075, Hubei, Peoples R China.;[Qiao, Jie; He, Ruyi; Qiao, J] Wuhan Polytech Univ, Sch Life Sci & Technol, Pilot Base Food Microbial Resources Utilizat Hubei, Wuhan 430023, Hubei, Peoples R China.;[Qiao, Jie; Qiao, J] Zhengzhou Univ, Affiliated Hosp 1, Dept Oral & Maxillofacial Surg, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450001, Peoples R China.
通讯机构：
[Qiao, J ] W;[Mao, WX; Liu, Y ] H;Hubei Univ, Sch Life Sci, State Key Lab Biocatalysis & Enzyme Engn, Wuhan 430042, Hubei, Peoples R China.;BravoVax Co Ltd, Wuhan 430075, Hubei, Peoples R China.;Wuhan Polytech Univ, Sch Life Sci & Technol, Pilot Base Food Microbial Resources Utilizat Hubei, Wuhan 430023, Hubei, Peoples R China.
摘要：
The CRISPR/Cas12a system has revolutionized molecular diagnostics, yet the direct detection of RNA, particularly those with complex structures, remains a significant challenge. Here, we present an updated SCas12a system, termed SCas12aV2, which enables precise, amplification-free detection of highly structured RNA molecules. By optimizing the length of scaffold RNA, targeting asymmetric structures, and utilizing dsDNA-ssDNA hybrid activators, we have significantly reduced steric hindrance in the detection system, thereby markedly enhancing both sensitivity and kinetics compared to traditional DNA activators. The SCas12aV2 assay achieves a detection limit of 246 aM for pooled activators and 10 pM for single-site targeting, demonstrating high specificity for single nucleotide polymorphisms (SNPs). It successfully identifies viable bacteria and SARS-CoV-2 infections in clinical samples. The assay is versatile and can be applied to various Cas12a orthologs, including thermostable CtCas12a. This work advances molecular diagnostics by improving the accuracy and efficiency of RNA detection. This study presents an updated split Cas12a system that enables amplification-free detection of the RNA with complex structures, thereby advancing point-of-care diagnostics.
摘要：
Total starch granule-associated proteins (tGAP), including granule-channel (GCP) and granule-surface proteins (GSP), alter the physicochemical properties of starches. Quinoa starch (QS) acts as an effective emulsifier in Pickering emulsion. However, the correlation between the tGAP and the emulsifying capacity of QS at different scales remains unclear. Herein, GCP and tGAP were selectively removed from QS, namely QS-C and QS-A. Results indicated that the loss of tGAP increased the water permeability and hydrophilicity of the starch particles. Mesoscopically, removing tGAP decreased the diffusion rate and interfacial viscous modulus. Particularly, GSP had a more profound impact on the interfacial modulus than GCP. Microscopically and macroscopically, the loss of tGAP endowed QS with weakened emulsifying ability in terms of emulsions with larger droplet size and diminished rheological properties. Collectively, this work demonstrated that tGAP played an important role in the structural and interfacial properties of QS molecules and the stability of QS-stabilized emulsions.
期刊：
CURRENT MEDICINAL CHEMISTRY,2025年32:1-13 ISSN：0929-8673
作者机构：
[Wenbin Liu] College of Medicine and Health Science, Wuhan Polytechnic
University, Wuhan, 430023, China;[Muhammad Umer] Research Center of Forest
Ecology, Institute for Forest Resources and Environment of Guizhou and Forestry College, Guizhou University,
Guiyang, 550025, China;[Yang Xu] Wuhan Polytechnic University School of Modern Industry for Selenium Science and Engineering Wuhan China;[Jixin Chen; Yi He; Shiya Wei; Zhangqian Wang; Chao Gao] National R&[Jixin Chen; Yi He; Shiya Wei; Zhangqian Wang; Chao Gao] D Center for Se-rich Agricultural Products Processing, Hubei Engineering Research Center
for Deep Processing of Green Se-rich Agricultural Products, School of Modern Industry for Selenium Science
and Engineering, Wuhan Polytechnic University, Wuhan, 430023, China
摘要：
Introduction: G-quadruplexes (G4s) are non-classical high-level structures that are formed by DNA/RNA sequences and have been a promising target for developing antitumor drugs. However, it is still a challenge to find a ligand that binds to a particular G4 with selectivity. Telomeric multimeric G4s are more accessible for screening for specific ligands due to their higher-order structure compared with telomeric monomeric G4s.<&wdkj&>Methods : In this study, the natural product berberine was found to exhibit a higher selectivity for telomeric multimeric G4 in comparison with other G4s. The mechanism of interaction between telomeric G4s and berberine was further investigated by fluorescence spectra measurements, job plot analysis, and UV titrations. We found that there are three binding sites for berberine on telomeric dimeric G-quadruplex Tel45, which are located at the 5' and 3' terminal G-quartet surfaces and the pocket between the two quadruplex units of Tel45. It was worth noting that the berberine preferred to interact within the interfacial cavity between two G4 units.<&wdkj&>Results : Moreover, via dynamic light scattering (DLS) and native polyacrylamide gel electrophoresis (Native-PAGE) assays, it was found that the particle size of the telomeric multimeric G4s conformation was significantly increased by the addition of berberine. In contrast, the particle sizes of Tel21 did not change significantly after the addition of berberine. An immunofluorescence assay indicated that berberine induced the formation of endogenous telomeric G4 structures along with the related telomeric DNA damage response.<&wdkj&>Conclusion: This study provides a hypothetical basis for the development of natural products targeting telomeric G4 as antitumor drugs.
关键词：
Image deblurring;self-attention mechanism;lightweight model;hinge loss function
摘要：
The acquisition of clear images is a critical aspect in various fields including computer vision, aerial detection, and medical imaging. The issue of image blur caused by object motion poses a challenge in obtaining clear images. To address this, an improved AT-DGAN network model is proposed in this paper. This model integrates the pyramid generator module of the DeblurGAN-v2 network with a self-attention mechanism. The feature pyramid is employed for image feature extraction and representation, while the self-attention mechanism dynamically adjusts the weight of important features in each pyramid layer and performs weighted fusion, thereby compensating for the information loss during feature extraction in the feature pyramid network. Additionally, a hinge loss function is designed for the proposed model to balance the discriminator and the generator, enhancing the stability and training efficiency of the generative adversarial network. The experimental results show that compared to other algorithms of the same type, this improved algorithm has increased the Peak Signal-to-Noise Ratio (PSNR) and Structural Similarity Index (SSIM) of restored images by 0.58 dB and 1.5%, respectively.
通讯机构：
[Liu, P ; Liu, Y ; Liu, P] T;TianGong Univ, Sch Mat Sci & Engn, State Key Lab Separat Membranes & Membrane Proc, Tianjin 300387, Peoples R China.;Tiangong Univ, Sch Chem, Tianjin 300387, Peoples R China.;Wuhan Polytech Univ, Sch Chem & Environm Engn, Wuhan 430023, Peoples R China.;Tiangong Univ, Cangzhou Inst, Cangzhou 061000, Peoples R China.
摘要：
Correction for ‘Potentiating light-harvesting tactics through an A–D–A structure: repolarization of tumor-associated macrophages through phototherapy’ by Pai Liu et al. , J. Mater. Chem. B , 2024, 12 , 7870–7878, https://doi.org/10.1039/D4TB00814F.
