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Point-of-care SERS-based ML diagnosis of head and neck cancer via cerumen analysis

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成果类型:
期刊论文
作者:
Edoardo Farnesi;Rustam Guliev;Chen Liu;Jonas Ballmaier;Orlando Guntinas-Lichius;...
通讯作者:
Dana Cialla-May
作者机构:
[Michael Schmitt] Institute of Physical Chemistry (IPC) and Abbe Center of Photonics (ACP), Friedrich Schiller University Jena, Member of the Leibniz Centre for Photonics in Infection Research (LPI), Jena, Germany
[Rustam Guliev] Leibniz Institute of Photonic Technology, Member of Leibniz Health Technologies, Member of the Leibniz Centre for Photonics in Infection Research (LPI), Jena, Germany
[Jonas Ballmaier; Orlando Guntinas-Lichius] Department of Otorhinolaryngology-Head and Neck Surgery, Jena University Hospital, Jena, Germany
[Chen Liu] School of Food Science and Engineering, Wuhan Polytechnic University, Wuhan, China
[Edoardo Farnesi; Juergen Popp; Dana Cialla-May] Institute of Physical Chemistry (IPC) and Abbe Center of Photonics (ACP), Friedrich Schiller University Jena, Member of the Leibniz Centre for Photonics in Infection Research (LPI), Jena, Germany<&wdkj&>Leibniz Institute of Photonic Technology, Member of Leibniz Health Technologies, Member of the Leibniz Centre for Photonics in Infection Research (LPI), Jena, Germany
通讯机构:
[Dana Cialla-May] I
Institute of Physical Chemistry (IPC) and Abbe Center of Photonics (ACP), Friedrich Schiller University Jena, Member of the Leibniz Centre for Photonics in Infection Research (LPI), Jena, Germany<&wdkj&>Leibniz Institute of Photonic Technology, Member of Leibniz Health Technologies, Member of the Leibniz Centre for Photonics in Infection Research (LPI), Jena, Germany
语种:
英文
期刊:
npj Biosensing
ISSN:
3004-8656
年:
2025
卷:
2
期:
1
机构署名:
本校为其他机构
院系归属:
食品科学与工程学院
摘要:
Early detection of head and neck cancer (HNC) is critical for improving prognosis and survival rates. Many cases are diagnosed at advanced stages due to subtle initial symptoms and the complexity of the head and neck anatomy, which complicates clinical examination and biopsy procedures. Therefore, there is an urgent need for non-invasive, reliable, and rapid diagnostic methods suitable for point-of-care (POC) settings. In this study, we applied surface-enhanced Raman spectroscopy (SERS) to develop a rapid screening method for HNC diagnosis using cerumen as the medium. The study aimed to utiliz...

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