Modifying effects of prenatal exposure to rare earth elements on birth outcomes through maternal thyroid function in early pregnancy

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成果类型：

期刊论文

作者：

Wang, Sisi;Li, Jingguang;Wu, Yongning;Liu, Xin;Zhang, Lei

通讯作者：

Liu, X;Zhang, L

作者机构：

[Wang, Sisi; Wu, Yongning; Liu, Xin] Wuhan Polytech Univ, Coll Food Sci & Engn, Hubei Key Lab Proc & Transformat Agr Prod, Wuhan 430023, Hubei, Peoples R China.

[Li, Jingguang; Wu, Yongning; Zhang, Lei] Chinese Acad Med Sci, Peking Union Med Coll, Dept Nutr & Food Safety, Res Unit Food Safety, Beijing 100010, Peoples R China.

[Li, Jingguang; Wu, Yongning; Zhang, Lei] China Natl Ctr Food Safety Risk Assessment, NHC Key Lab Food Safety Risk Assessment, Beijing 100010, Peoples R China.

[Zhang, Lei] China Natl Ctr Food Safety Risk Assessment CFSA, NHC Key Lab Food Safety Risk Assessment, Beijing 100021, Peoples R China.

[Liu, Xin] Wuhan Polytech Univ, 68 Xuefu South Rd, Wuhan 430023, Hubei, Peoples R China.

通讯机构：

[Zhang, L ] C

[Liu, X ] W

Wuhan Polytech Univ, 68 Xuefu South Rd, Wuhan 430023, Hubei, Peoples R China.

China Natl Ctr Food Safety Risk Assessment CFSA, NHC Key Lab Food Safety Risk Assessment, Beijing 100021, Peoples R China.

语种：

英文

关键词：

Fetal growth;Mediation analysis;Rare earth elements;Thyroid homeostasis

期刊：

Environmental Pollution

ISSN：

0269-7491

年：

2025

卷：

366

页码：

125507

DOI：

10.1016/j.envpol.2024.125507

基金类别：

CRediT authorship contribution statement Sisi Wang: Writing – original draft, Visualization, Software, Formal analysis. Jingguang Li: Writing – review & editing, Resources. Yongning Wu: Writing – review & editing, Resources. Xin Liu: Writing – review & editing, Supervision, Project administration, acquisition. Lei Zhang: Writing – review & editing, Validation, Methodology, acquisition.

机构署名：

本校为第一且通讯机构

院系归属：

食品科学与工程学院

摘要：

The potential health effects of exposure to rare earth elements (REEs) remain largely unexplored. This prospective cohort study aimed to elucidate the association between early pregnancy REE exposure and maternal thyroid function, as well as neonatal birth outcomes, in a cohort of pregnant women in Beijing, China. Additionally, the study explored the mediating role of thyroid homeostasis in the effects of REE exposure. Serum concentrations of fifteen REEs, along with Free Thyroxine (FT4), Thyroid Stimulating Hormone (TSH), and Thyroid Peroxidas...

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Modifying effects of prenatal exposure to rare earth elements on birth outcomes through maternal thyroid function in early pregnancy

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