期刊论文

Lai, YJ

英文

Toxics

2305-6304

2025

13

5

413-

10.3390/toxics13050413

This study was supported by Wuhan Polytechnic University Industry-Academia-Research Project (Project No.: whpu-2023-kj-2709). Yong Guo, Gantong Guo and Tao He were employed by Sinagri YingTai Bio-peptide Co., Ltd. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The funding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, and in the decision to publish the results.

本校为通讯机构

Sublancin, an S-linked antimicrobial (glycol) peptide produced by Bacillus subtilis, has emerged as a novel and promising veterinary drug due to its unique antibacterial mechanism, low risk of resistance, and properties that modulate the immune system, reduce inflammation, and promote gut health. This study comprehensively assessed the subchronic (90-day) and chronic (180-day) toxicity of Sprague-Dawley (SD) rats, following the guidelines issued by the Ministry of Agriculture of China. Rats were orally administered sublancin at doses of 2000, 10,000, or 50,000 mg/kg feed, representing 1666-500...