期刊论文

Wu, Jin-E

英文

Applied Biochemistry and Biotechnology

0273-2289

2017

182

1

411-427

10.1007/s12010-016-2335-x

The authors acknowledge the financial support from the National Natural Science Foundation of China (31302139).

本校为第一且通讯机构

The aims of our study were to evaluate the effects of Saccharomyces boulardii (S. boulardii) on deoxynivalenol (DON)-induced injury in porcine alveolar macrophage cells (PAMCs) and to explore the underlying mechanisms. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, flow cytometric analysis, ELISA, qRT-PCR, and western blot were performed to assess whether S. boulardii could prevent DON-induced injury by p38 mitogen-activated protein kinase (p38 MAPK) signal pathway. The results showed that pretreatment with 8μM DON c...