Berberine Facilitates Extinction and Prevents the Return of Fear

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Huang, Shihao;Zhou, Yu;Wu, Feilong;Shi, Cuijie;Yan, He;...

通讯作者：

Yang, C.

作者机构：

[Huang, Shihao; Yang, Chang; Luo, Yixiao; Shi, Cuijie; Wu, Feilong] Hunan Normal Univ, Sch Med, Key Lab Mol Epidemiol Hunan Prov, Changsha, Peoples R China.

[Zhou, Yu] Yiyang Med Coll, Yiyang, Peoples R China.

[Chen, Liangpei; Yan, He] Cent South Univ, Sch Basic Med Sci, Dept Forens Sci, Changsha, Peoples R China.

[Yang, Chang; Luo, Yixiao] Hunan Normal Univ, Affiliated Hosp 1, China Hunan Prov Peoples Hosp, Changsh, Peoples R China.

通讯机构：

Key Laboratory of Molecular Epidemiology of Hunan Province, School of Medicine, Hunan Normal University, Changsha, China

语种：

英文

关键词：

berberine;extinction;fear memory;contextual fear conditioning;PTSD

期刊：

Frontiers in Pharmacology

ISSN：

1663-9812

年：

2022

卷：

DOI：

10.3389/fphar.2021.748995

基金类别：

Natural Science Foundation of China [81771434]; Outstanding Innovative Youth Training Program of Changsha [kq2106032]

机构署名：

本校为其他机构

摘要：

Exposure to a catastrophic event or intense stimulation can trigger fear memories, and the threatening memories persist even over a lifetime. Exposure therapy is based on extinction learning and is widely used to treat fear-related disorders, but its effect on remote fear memory is modest. Berberine, an isoquinoline alkaloid derived from Coptis chinensis or Berberis spp., has been recently reported to exert a diversity of pharmacological effects on the central nervous system, such as facilitating extinction of drug memory. Here, we explored the...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Berberine Facilitates Extinction and Prevents the Return of Fear

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问