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Effective protective agents against organ toxicity of deoxynivalenol and their detoxification mechanisms: A review

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成果类型:
期刊论文
作者:
Wang, Pengju;Yao, Qin;Meng, Xiangwen;Yang, Xiaosong;Wang, Xu;...
通讯作者:
Liu, AM
作者机构:
[Yao, Qin; Liu, Aimei; Meng, Xiangwen; Yang, Xiaosong; Wang, Pengju] Hubei Univ Sci & Technol, Med Res Inst, Xianning Med Coll, Xianning 437100, Peoples R China.
[Wang, Xu] Huazhong Agr Univ, Natl Reference Lab Vet Drug Residues HZAU, Wuhan 430070, Hubei, Peoples R China.
[Wang, Xu] Huazhong Agr Univ, MAO Key Lab Detect Vet Drug Residues, Wuhan 430070, Hubei, Peoples R China.
[Lu, Qirong] Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Peoples R China.
通讯机构:
[Liu, AM ] H
Hubei Univ Sci & Technol, Med Res Inst, Xianning Med Coll, Xianning 437100, Peoples R China.
语种:
英文
关键词:
Deoxynivalenol;Detoxification mechanisms;Organ toxicity;Protective agent
期刊:
Food and Chemical Toxicology
ISSN:
0278-6915
年:
2023
卷:
182
页码:
114121
基金类别:
Hubei University of Science and Technology [BK202315, 2022YKY17]; Hubei University of Science and Technology; Hubei Provincial Natural Science Foundation Programme [2023AFB537]
机构署名:
本校为其他机构
院系归属:
动物科学与营养工程学院
摘要:
Deoxynivalenol (DON) is one of the most prevalent mycotoxins in feed, which causes organ toxicity in animals. Therefore, reducing DON-induced organ toxicity can now be accomplished effectively using protective agents. This review provides an overview of multiple studies on a wide range of protective agents and their molecular mechanisms against DON organ toxicity. Protective agents include plant extracts, yeast products, bacteria, peptides, enzymes, H2, oligosaccharides, amino acids, adsorbents, vitamins and selenium. Among these, biological detoxification of DON using microorganisms to reduce...

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