atelocollagen;collagen;fluorescein isothiocyanate;telopeptide;tropocollagen;Article;collagen fibril;extracellular matrix;grass carp;morphology;nonhuman;pig;polyacrylamide gel electrophoresis;priority journal;scanning electron microscopy;skin;viscoelasticity
This research was supported by the National Natural Science Foundation of China (No. 21676208, and 21706201), the Hubei Provincial Nature Science Foundation of China (2018CFA030), and the Wuhan Morning Light Plan of Youth Science and Technology (No. 2017050304010326).
机构署名：
本校为第一且通讯机构
院系归属：
化学与环境工程学院
摘要：
Xenogeneic collagen co-assembly (XCCA) is a novel and efficient strategy for improving and regulating the performance of collagen assembled products. However, the effect of collagen molecular structures on XCCA has long been neglected and remains unclear. Herein, we investigated the telopeptide effect of collagen on XCCA by employing grass carp skin collagen (GCSC) with two different structures (tropocollagen and atelocollagen) and porcine skin collagen (PSC). Kinetic analysis showed that the co-assembly rate of PSC and grass carp skin atelocollagen (AC-GCSC) was faster than that of PSC and gr...
