\"Multi-in-One\" Yolk-Shell Structured Nanoplatform Inducing Pyroptosis and Antitumor Immune Response Through Cascade Reactions - 成果

首页 > 成果 > 详情

"Multi-in-One" Yolk-Shell Structured Nanoplatform Inducing Pyroptosis and Antitumor Immune Response Through Cascade Reactions

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Wang, Yu-Ying;Li, Shu-Lan;Zhang, Xiao-Yang;Jiang, Feng-Lei;Guo, Qing-Lian;...

通讯作者：

Liu, Y;Guo, QL;Jiang, P

作者机构：

[Wang, Yu-Ying; Jiang, Feng-Lei; Liu, Yi; Zhang, Xiao-Yang] Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China.

[Li, Shu-Lan] Wuhan Polytech Univ, Sch Chem & Environm Engn, Wuhan 430023, Peoples R China.

[Guo, Qing-Lian] Wuhan Univ, Dept Clin Lab, Zhongnan Hosp, Wuhan 430071, Peoples R China.

[Jiang, Peng; Jiang, P] Wuhan Univ, Zhongnan Hosp, Sch Pharmaceut Sci, Dept Orthoped Trauma & Microsurg, Wuhan 430071, Peoples R China.

[Jiang, Peng; Jiang, P] Hubei Jiangxia Lab, Wuhan 430200, Peoples R China.

通讯机构：

[Guo, QL ; Liu, Y ; Jiang, P ] W

Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China.

Wuhan Univ, Dept Clin Lab, Zhongnan Hosp, Wuhan 430071, Peoples R China.

Wuhan Univ, Zhongnan Hosp, Sch Pharmaceut Sci, Dept Orthoped Trauma & Microsurg, Wuhan 430071, Peoples R China.

Hubei Jiangxia Lab, Wuhan 430200, Peoples R China.

语种：

英文

关键词：

cascade reactions;chemodynamic therapy;cuproptosis;immunogenic cell death;pyroptosis

期刊：

Small

ISSN：

1613-6810

年：

2024

页码：

e2400254

DOI：

10.1002/smll.202400254

基金类别：

National Natural Science Foundation of China; Young Top-notch Talent Cultivation Program of Hubei Province, Science and Technology Plans of Tianjin [21ZYJDJC00050]; Large-Scale Instrument and Equipment Sharing Foundation of Wuhan University; [U23A2089]; [22074113]; [22203061]; [22073070]

机构署名：

本校为其他机构

院系归属：

化学与环境工程学院

摘要：

Pyroptosis, a new mode of regulatory cell death, holds a promising prospect in tumor therapy. The occurrence of pyroptosis can trigger the release of damage-associated molecular patterns (DAMPs) and activate the antitumor immune response. Moreover, enhancing intracellular reactive oxygen species (ROS) generation can effectively induce pyroptosis. Herein, an integrated nanoplatform (hCZAG) based on zeolitic imidazolate framework-8 (ZIF-8) with Cu2+ and Zn2+ as active nodes and glucose oxidase (GOx) loading is constructed to evoke pyroptosis. GOx can effectively elevate intracellular hydrogen pe...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

"Multi-in-One" Yolk-Shell Structured Nanoplatform Inducing Pyroptosis and Antitumor Immune Response Through Cascade Reactions

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问