Vibrio parahaemolyticus is a common foodborne pathogen with drug-resistant strains now widespread. The use of phages to control resistant bacteria is a promising means of reducing public health pressure. In this study, V. parahaemolyticus phage 460s1 was isolated, which was active over a wide range of temperature (30-50 degrees C) and pH (3-10). It exhibited a specific host range, lysing 16 of the 23 strains of V. parahaemolyticus. The phage 460s1 can effectively inhibit the growth of V. parahaemolyticus in shrimp at 15 degrees C and 25 degrees C, and bacterial count decreased by 3.46 log colo...
