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Dual-modified selenium nanoparticles for the synergistic treatment of breast cancer

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成果类型:
期刊论文
作者:
Zhu, Lian*;Mi, Peng;Yu, Ze-Long;Zhang, Qing-He;Liao, Li-Xia;...
通讯作者:
Zhu, Lian;Wei, BM;Wang, HB
作者机构:
[Zhu, Lian; Wei, Ben-Mei; Mi, Peng; Zhang, Qing-He; Yu, Ze-Long; Liao, Li-Xia] Wuhan Polytech Univ, Sch Chem & Environm Engn, Wuhan 430023, Peoples R China.
[Wang, Hai-Bo] Hubei Engn Univ, Coll Life Sci & Technol, Hubei Key Lab Qual Control Characterist Fruits & V, Xiaogan 432000, Peoples R China.
通讯机构:
[Zhu, L; Wei, BM ] W
[Wang, HB ] H
Wuhan Polytech Univ, Sch Chem & Environm Engn, Wuhan 430023, Peoples R China.
Hubei Engn Univ, Coll Life Sci & Technol, Hubei Key Lab Qual Control Characterist Fruits & V, Xiaogan 432000, Peoples R China.
语种:
英文
关键词:
Selenium nanoparticles;Modification;DOX;Synergistic effect;Antitumor
期刊:
Materials Today Chemistry
ISSN:
2468-5194
年:
2025
卷:
43
页码:
102451
基金类别:
CRediT authorship contribution statement Lian Zhu: Writing – review & editing, Writing – original draft, acquisition, Conceptualization. Peng Mi: Methodology, Investigation. Ze-Long Yu: Investigation, Formal analysis. Qing-He Zhang: Investigation, Data curation. Li-Xia Liao: Project administration. Ben-Mei Wei: Supervision. Hai-Bo Wang: Writing – review & editing, Supervision, acquisition. Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interestsHai-Bo Wang reports financial support was provided by National Natural Science Foundation of China. Lian Zhu reports financial support was provided by Natural Science Foundation of Hubei Province. Lian Zhu reports financial support was provided by Open Project of Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Acknowledgements This work was financially supported by Open Project of Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, Hubei University, Wuhan, 430062, PR, China (No. KLSAOFM2314), National Natural Science Foundation of China (No. 22178277), and Natural Science Foundation of Hubei Province (No. 2024AFB919).
机构署名:
本校为第一且通讯机构
院系归属:
化学与环境工程学院
摘要:
High stability of selenium nanoparticles (SeNPs) is crucial for preserving their biochemical properties. Currently, surface modification is one of the most effective routes to improve the stability of nanoparticles. Herein, we synthesized SeNPs through a mild reduction reaction at room temperature. Subsequently, the SeNPs were simultaneously coated with polyvinylpyrrolidone (PVP) and glucose to improve stability, the obtained composite was abbreviated as PG-SeNPs. Results demonstrated that PG-SeNPs displayed excellent stability without any coag...

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