Self-assembly is one of the most vital molecular behaviors of natural collagen, which plays a prominent role in the design and fabrication of collagen-based biomaterials. However, an efficient and sensitive assay for monitoring collagen self-assembly is still lacking. Herein, we developed a quantum dot (QD)-based fluorescence sensing platform and applied it to monitor collagen self-assembly. Before collagen self-assembly, we observed a strong fluorescent signal when ZnCdSe/ZnS QDs were introduced to grass carp skin collagen (GCSC). After self-a...
