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Response of Selenium and Selenogenome in Immune Tissues to LPS-Induced Inflammatory Reactions in Pigs

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成果类型:
期刊论文
作者:
Sun, Lv-Hui;Pi, Ding-An;Zhao, Ling;Wang, Xiu-Ying;Zhu, Luo-Yi;...
通讯作者:
Liu, Yu-Lan
作者机构:
[Zhu, Luo-Yi; Zhao, Ling; Sun, Lv-Hui; Qi, De-Sheng] Huazhong Agr Univ, Dept Anim Nutr & Feed Sci, Coll Anim Sci & Technol, Wuhan 430070, Hubei, Peoples R China.
[Wang, Xiu-Ying; Pi, Ding-An; Liu, Yu-Lan] Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan, Peoples R China.
通讯机构:
[Liu, Yu-Lan] W
Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan, Peoples R China.
语种:
英文
关键词:
Selenium;Selenoprotein;LPS;Inflammatory reaction;Pigs
期刊:
Biological Trace Element Research
ISSN:
0163-4984
年:
2017
卷:
177
期:
1
页码:
90-96
基金类别:
Chinese Natural Science FoundationNational Natural Science Foundation of China (NSFC) [31501987, 31422053, 31372318]
机构署名:
本校为通讯机构
院系归属:
动物科学与营养工程学院
摘要:
Circulating concentration of the essential trace element selenium (Se) was significantly lower in inflammatory disorders. Although Se plays physiological roles mainly through the function of 25 selenoproteins, the response of the selenogenome in immune tissues during inflammatory reactions remains unclear. The objective of this study was to determine the Se retention and selenogenome expression in immune tissues during the lipopolysaccharide (LPS)-induced inflammatory response in porcine. A total of 12 male pigs were randomly divided into two groups and injected with LPS or saline. After 4 h p...

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