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Hepatoprotective effects of peach gum polysaccharides against alcoholic liver injury: moderation of oxidative stress and promotion of lipid metabolism

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成果类型:
期刊论文
作者:
Zhou, Bingjie;Liu, Pinpin;Yao, Xiangao;Cao, Huijie;Zhu, Hang;...
通讯作者:
Gong, ZY
作者机构:
[Liu, Yan; Zhu, Hang; Gong, Zhiyong; Gong, ZY; Wu, Yongning; Wang, Qiao; Liu, Pinpin; Yao, Xiangao; Zhou, Bingjie; Fang, Min] Wuhan Polytech Univ, Key Res Inst Humanities & Social Sci Hubei Prov, Hubei Key Lab Proc & Transformat Agr Prod, Key Lab Deep Proc Major Grain & Oil,Food Safety Re, Wuhan, Peoples R China.
[Cao, Huijie] Suizhou Ctr Dis Control & Prevent, Wuhan, Hubei, Peoples R China.
[Wu, Yongning] Chinese Acad Med Sci, China Natl Ctr Food Safety Risk Assessment, NHC Key Lab Food Safety Risk Assessment, Food Safety Res Unit 2019RU014, Beijing, Peoples R China.
通讯机构:
[Gong, ZY ] W
Wuhan Polytech Univ, Key Res Inst Humanities & Social Sci Hubei Prov, Hubei Key Lab Proc & Transformat Agr Prod, Key Lab Deep Proc Major Grain & Oil,Food Safety Re, Wuhan, Peoples R China.
语种:
英文
关键词:
peach gum polysaccharides;structural analysis;antioxidant activity;alcoholic liver damage;metabolomic
期刊:
FRONTIERS IN NUTRITION
ISSN:
2296-861X
年:
2024
卷:
10
机构署名:
本校为第一且通讯机构
院系归属:
食品科学与工程学院
摘要:
Natural polysaccharides extracted from plants have received increasing attention due to their rich bioactivity. In our study, peach gum polysaccharides (PGPs) were extracted by water extraction-alcohol precipitation method. PGPs are typical pyranose polysaccharides with a mean molecular weight of 3.68 x 106 g/mol. The antioxidant activity and hepatoprotective capacity of PGPs were studied. In vitro, assays showed that PGPs scavenged DPPH, OH, and O2- in a dose-dependent manner. PGPs exhibited antioxidative properties against alcohol-induced HL7702 cells, as evidenced by the normalization of MD...

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