Baicalin-aluminum complex on the regulation of IPEC-1 infected with enterotoxigenic Escherichia coli

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成果类型：

期刊论文

作者：

Ye, Chun;Chen, Yuqian;Yu, Ruixue;Zhao, Ming;Yin, Ronghua;...

通讯作者：

Qiu, YS

作者机构：

[Yin, Ronghua; Liu, Yu; Zhao, Ming; Ye, Chun; Qiu, Yinsheng; Chen, Yuqian; Yu, Ruixue; Wu, Zhongyuan; Fu, Shulin] Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430000, Peoples R China.

[Yin, Ronghua; Liu, Yu; Zhao, Ming; Ye, Chun; Qiu, Yinsheng; Chen, Yuqian; Yu, Ruixue; Wu, Zhongyuan; Fu, Shulin] Hubei Collaborat Innovat Ctr Anim Nutr & Feed Safe, Wuhan 430000, Peoples R China.

[Qiu, Yinsheng] Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Peoples R China.

通讯机构：

[Qiu, YS ] W

Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Peoples R China.

语种：

英文

关键词：

Baicalin-aluminum complex;Diarrhea;Enterotoxigenic Escherichia coli;IPEC-1;Piglet

期刊：

Heliyon

ISSN：

2405-8440

年：

2024

卷：

期：

DOI：

10.1016/j.heliyon.2024.e33038

基金类别：

Key Research and Development Plan of Hubei Province [2022BBA0055]; Scientific Research Projects in Hubei Provincial Department of Education [D20221607]; National Natural Science Foundation of China [32002333]; Research and Innovation Initiatives of WHPU [2018Y03]

机构署名：

本校为第一且通讯机构

院系归属：

动物科学与营养工程学院

摘要：

Enterotoxigenic Escherichia coli (ETEC) is the main bacterial cause of diarrhea in weaned piglets. Baicalin-aluminum (BA) complex is the main active ingredient of Scutellaria baicalensis Georgi extracted-aluminum complex, which has been used to treat diarrhea in weaning piglets, however the underlying mechanism remains unclear. To investigate the effects of the BA complex on the regulation of porcine intestinal epithelial (IPEC-1) cells infected with ETEC, IPEC-1 cells were incubated with an ETEC bacterial strain at a multiplicity of infection of 1 for 6 h and then treated with different conce...

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Baicalin-aluminum complex on the regulation of IPEC-1 infected with enterotoxigenic Escherichia coli

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