Effects of Mechanical Stress Stimulation on Function and Expression Mechanism of Osteoblasts

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成果类型：

期刊论文

作者：

Liu, Pan;Tu, Ji;Wang, Wenzhao;Li, Zheng;Li, Yao;...

通讯作者：

Zhang, ZD;Yu, XP

作者机构：

[Zhang, Zhengdong; Li, Yao; Liu, Pan] Chengdu Med Coll, Sch Clin Med, Chengdu, Peoples R China.

[Zhang, Zhengdong; Li, Yao; Liu, Pan] Chengdu Med Coll, Affiliated Hosp 1, Chengdu, Peoples R China.

[Tu, Ji] Univ New South Wales, St George & Sutherland Clin Sch, Spine Labs, Sydney, NSW, Australia.

[Wang, Wenzhao] Sichuan Univ, Dept Orthped, West China Hosp, Chengdu, Peoples R China.

[Li, Zheng] Peoples Hosp Jiulongpo Dist, Chongqing, Peoples R China.

通讯机构：

[Yu, XP ; Zhang, ZD ] C

Chengdu Med Coll, Sch Clin Med, Chengdu, Peoples R China.

Chengdu Med Coll, Affiliated Hosp 1, Chengdu, Peoples R China.

Chengdu Med Coll, Sch Publ Hlth, Chengdu, Peoples R China.

Chengdu Med Coll, Basic Med Coll, Chengdu, Peoples R China.

语种：

英文

关键词：

mechanical stress;stimulation;function;expression mechanism;osteoblasts

期刊：

Frontiers in Bioengineering and Biotechnology

ISSN：

2296-4185

年：

2022

卷：

DOI：

10.3389/fbioe.2022.830722

机构署名：

本校为通讯机构

摘要：

Osteoclasts and osteoblasts play a major role in bone tissue homeostasis. The homeostasis and integrity of bone tissue are maintained by ensuring a balance between osteoclastic and osteogenic activities. The remodeling of bone tissue is a continuous ongoing process. Osteoclasts mainly play a role in bone resorption, whereas osteoblasts are mainly involved in bone remodeling processes, such as bone cell formation, mineralization, and secretion. These cell types balance and restrict each other to maintain bone tissue metabolism. Bone tissue is very sensitive to mechanical stress stimulation. Unl...

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Effects of Mechanical Stress Stimulation on Function and Expression Mechanism of Osteoblasts

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