期刊论文

Yun Fan<&wdkj&>Hong-Xun Wang

英文

Food Research International

0963-9969

2021

143

110307

10.1016/j.foodres.2021.110307

Exogenous antioxidants, including vitamins, carotenoids, flavonoids, phenolic acids, polysaccharides, peptides and proteins, can be obtained from various foods (Cömert & Gökmen, 2018; B. Chen & Xu, 2019). Their antioxidative effects in vivo are mostly assessed in rodent models by analyzing the markers associated with oxidative damage or antioxidative defense in blood and tissues (Apak et al., 2016, Ghezzi, 2020). These markers are mainly biochemical parameters, such as RS levels, oxidative

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Dietary supplementation with antioxidants provides health benefits by preventing diseases caused by oxidative stress and damage. Consequently, there has been growing interest in the study of antioxidative foods and their active ingredients. Oxidative stress and antioxidative responses are mechanistically conserved from Drosophila to mammals. Therefore, as a well-established model organism with a short life cycle and advantages of genetic manipulation, the fruit fly has been increasingly employed to assess functions of antioxidants in vivo. In this review, the antioxidative defense mechanisms, ...