To study the preventive effect of curcumin(Curcumin,CUR)on acute liver injury induced by car-bon tetrachloride(CCl4)in mice and its mechanism.ICR male mice were randomly divided into normal con-trol group,model group,curcumin(50,100,200 mg/kg)groups and bifendate(150 mg/kg).The curcumin groups and the bifendate group were given the corresponding dose of drugs by gavage,once a day for 8 days.After the last administration,except the mice in the normal control group,the other mice were intrap-eritoneally injected with 0.1%CCl4 peanut oil solution,...
