期刊论文

Study on anti-gastric cancer mechanism of stigmasterol based on network pharmacology

中文

武汉轻工大学学报

2095-7386

2023

42

01

38-44

10.3969/j.issn.2095-7386.2023.01.006

湖北省自然科学基金项目(2022CFB429)。

本校为第一机构

豆甾醇是来源于食物中的一种植物不饱和甾醇,在胃癌防治中展现出良好的应用前景。基于网络药理学探讨豆甾醇抗胃癌的作用靶点及分子机制。借助PharmMapper数据库得到药物相关靶点,通过疾病数据库Genecard和OMIM(...展开更多 豆甾醇是来源于食物中的一种植物不饱和甾醇,在胃癌防治中展现出良好的应用前景。基于网络药理学探讨豆甾醇抗胃癌的作用靶点及分子机制。借助PharmMapper数据库得到药物相关靶点,通过疾病数据库Genecard和OMIM(Online Mendelian Inheritance in Man)获得胃癌相关靶点;对潜在标靶进行GO(Gene Ontology)、KEGG(Kyoto Encyclopedia of Genes and Genomes)富集分析得到相关作用...

Stigmasterol is a kind of plant unsaturated sterol from food,which shows good application prospect in the prevention and treatment of gastric cancer.Based on network pharmacology,this study investigated the target and molecular mechanism of stigmasterol against gastric ...MORE Stigmasterol is a kind of plant unsaturated sterol from food,which shows good application prospect in the prevention and treatment of gastric cancer.Based on network pharmacology,this study investigated the target and molecular mechanism of stigmasterol against gastric cancer.Drug related targets were obtained by PharmMa...