Oligomer Procyanidins from Lotus Seedpod Regulate Lipid Homeostasis Partially by Modifying Fat Emulsification and Digestion

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Li, Xiaopeng;Chen, Ya;Li, Shuyi;Chen, Mo;Xiao, Juan;...

通讯作者：

Sun, Zhida

作者机构：

[Sun, Zhida; Xie, Bijun; Chen, Ya; Li, Xiaopeng] Huazhong Agr Univ, Coll Food Sci & Technol, Wuhan 430070, Hubei, Peoples R China.

[Chen, Mo] Huazhong Agr Univ, Coll Informat, Wuhan 430070, Hubei, Peoples R China.

[Li, Shuyi] Wuhan Polytech Univ, Coll Food Sci & Engn, Wuhan 430023, Hubei, Peoples R China.

[Xiao, Juan] Hainan Univ, Coll Food Sci & Technol, Haikou 570228, Hainan, Peoples R China.

通讯机构：

[Sun, Zhida] H

Huazhong Agr Univ, Coll Food Sci & Technol, Wuhan 430070, Hubei, Peoples R China.

语种：

英文

关键词：

FFA release;LSOPC;digestion;hypolipidemic;sub-micrometer emulsion

期刊：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

ISSN：

0021-8561

年：

2019

卷：

期：

页码：

4524-4534

DOI：

10.1021/acs.jafc.9b01469

基金类别：

National Key Technologies Program of China [2012BAD31B03]

机构署名：

本校为其他机构

院系归属：

食品科学与工程学院

摘要：

Dietary polyphenols have shown hypolipidemic effects by reducing triglyceride absorption. The mechanisms may involve modifying fat emulsion during digestion in the gastrointestinal tract and suppressing lipase during hydrolysis in the small intestine. In an in vivo study, lotus seedpod oligomeric procyanidin (LSOPC) decreased total serum triglyceride and total cholesterol and elevated the high-density lipoprotein level in the hyperlipidemic rat model. In addition, LSOPC suppressed de novo lipogenesis-related gene expressions. In an in vitro study, the LSOPC-enriched emulsion decreased the mean...

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Oligomer Procyanidins from Lotus Seedpod Regulate Lipid Homeostasis Partially by Modifying Fat Emulsification and Digestion

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