National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81573577, 81403082, 81274057]; Natural Science Foundation of Taizhou Polytechnic College [1821819051]
机构署名:
本校为第一机构
摘要:
In this study, an optimal method used to extract Annona squamosa pericarp oil (ASPO) was established according to the response surface model. The yield of ASPO was 1.45%. 8 fatty acids were identified from ASPO by GC-MS. Among them, (9Z)-9-Octadecenoic acid was abundant and accounted for 49.65%. The anti-hepatoma activities of ASPO were investigated against SMMC-7721 cell line in vitro and H(22) cell line in vivo. Proteins associated with apoptosis in tumour tissue were quantified by western blot assay. The result revealed that ASPO had signif...