The present study was carried out to determine whether N-acetylcysteine (NAC) could modulate liver injury in a lipopolysaccharide (LPS)-challenged piglet model. For this purpose, eighteen piglets were randomly assigned to the control, LPS or NAC group. Piglets in the control and LPS groups were fed a basal diet, whereas those in the NAC group were fed the basal diet supplemented with 500mg/kg NAC. On days 10, 13 and 20 of the trial, the LPS-and NAC-treated piglets were intraperitoneally administered LPS (100μg/kg body weight), while the contro...
