Based on a single atom coupled to a fiber-coupled, chip-based microresonator [B. Dayan et al., Science 319, 1062 (2008)], we put forward a scheme to generate optical frequency combs at driving laser powers as low as a few nanowatts. Using state-of-the-art experimental parameters, we investigate in detail the influences of different atomic positions and taper-resonator coupling regimes on optical-frequency-comb generation. In addition to numerical simulations demonstrating this effect, a physical explanation of the underlying mechanism is presented. We find that the combination of the atom and ...