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Injury and mechanism of recombinant E-coli expressing STa on piglets colon

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成果类型:
期刊论文
作者:
Lv, Yang;Li, Xueni;Zhang, Lin;Shi, Yutao;Du, Linxiao;...
通讯作者:
Wu, Tao
作者机构:
[Wu, Tao; Gong, Joshua; Lv, Yang; Hou, Yongqing; Li, Xueni; Shi, Yutao; Ding, Binying; Du, Linxiao] Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Hubei, Peoples R China.
[Zhang, Lin] Chinese Acad Fishery Sci, Yangtze River Fisheries Res Inst, Wuhan 430070, Hubei, Peoples R China.
[Gong, Joshua] Agr & Agri Food Canada, Guelph Res & Dev Ctr, Guelph, ON N1G 5C9, Canada.
通讯机构:
[Wu, Tao] W
Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Hubei, Peoples R China.
语种:
英文
关键词:
colon;heat-stable enterotoxin A;piglet;recombinant escherichia coli
期刊:
Journal of Veterinary Medical Science
ISSN:
0916-7250
年:
2018
卷:
80
期:
2
页码:
205-212
基金类别:
Hubei Provincial Technology and Innovation Program [2017AHB062]; National Key Research and Development Program of China [2017YFD0500505]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31302089]; Agriculture and Agri-Food Canada A-base projectAgriculture & Agri Food Canada [J-001391]
机构署名:
本校为第一且通讯机构
院系归属:
动物科学与营养工程学院
摘要:
Enterotoxigenic Escherichia coli (ETEC) is primary pathogenic bacteria of piglet diarrhea, over two thirds of piglets diarrhea caused by ETEC are resulted from STa-producing ETEC strains. This experiment was conducted to construct the recombinant E. coli expressing STa and study the injury and mechanism of recombinant E. coli expressing STa on 7 days old piglets colon. Twenty-four 7 days old piglets were allotted to four treatments: control group, STa group (2 × 109 CFU E. coli LMG194-STa), LMG194 group (2 × 109 CFU E. coli LMG194) and K88 gr...

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