Flaxseed Oil Attenuates Intestinal Damage and Inflammation by Regulating Necroptosis and TLR4/NOD Signaling Pathways Following Lipopolysaccharide Challenge in a Piglet Model
State's Key Project of Research and Development Plan [2016YFD0501210]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31772615]; Project of the Hubei Provincial Department of Education [T201508]
机构署名：
本校为第一且通讯机构
院系归属：
动物科学与营养工程学院
摘要：
Scope Flaxseed oil is a rich source of α‐linolenic acid (ALA), which is the precursor of the long‐chain n‐3 polyunsaturated fatty acids (PUFAs), including docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). This study investigates the protective effect of flaxseed oil against intestinal injury induced by lipopolysaccharide (LPS). Materials and results Twenty‐four weaned pigs were used in a 2 × 2 factorial experiment with dietary treatment (5% corn oil vs 5% flaxseed oil) and LPS challenge (saline vs LPS). On day 21 of the experime...
