This project was supported by the National Natural Science Foundation of China (grant no. 21077082). The experiments conducted in this research comply with the current laws of the People’s Republic of China.
机构署名:
本校为第一机构
院系归属:
食品科学与工程学院
摘要:
Folic acid is a necessary micronutrient for normal human growth and development. Benzo(a)pyrene (BaP) is a ubiquitously distributed environmental pollutant and its metabolite, benzo(a)pyrene-diol-epoxide, is known to exert a strong teratogenic and carcinogenic effect on the body’s tissues and cells. The aim of this study was to investigate the mechanism by which folic acid can inhibit the toxic effects of BaP both in vivo and in vitro. We measured changes in 16HBE cell activity affected by the intervention of folic acid on BaP using the cell c...