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Bioinspired Lipase Immobilized Membrane for Improving Hesperidin Lipophilization

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成果类型:
期刊论文
作者:
Ming, Shanxiu;Li, Shuyi;Chen, Zhe;Chen, Xujun;Wang, Feifei;...
通讯作者:
Zhu, Z.;Barba, F.J.
作者机构:
[Li, Shuyi; Zhu, Zhenzhou; Chen, Xujun; Wang, Feifei; Chen, Zhe; Ming, Shanxiu] Wuhan Polytech Univ, Natl R&D Ctr Se Rich Agr Prod Proc Technol, Hubei Engn Res Ctr Deep Proc Green Se Rich Agr Pr, Sch Modern Ind Selenium Sci & Engn, Wuhan 430205, Peoples R China.
[Deng, Shaonan] Hubei Nanbai Shengtainongye Co Ltd, Enshi 445000, Peoples R China.
[Marszalek, Krystian] Prof Waclaw Browski Inst Agr & Food Biotechnol, Dept Fruit & Vegetable Prod Technol, State Res Inst, 36 Rakowiecka St, PL-02532 Warsaw, Poland.
[Marszalek, Krystian] Univ Rzeszow, Coll Nat Sci, Inst Food Technol & Nutr, Dept Food Technol & Human Nutr, Zelwerowicza 2D, PL-35601 Rzeszow, Poland.
[Zhang, Wenxiang] King Abdullah Univ Sci & Technol, Water Desalinat & Reuse Res Ctr, Biol & Environm Sci & Engn Div, Riyadh 11543, Saudi Arabia.
通讯机构:
[Zhenzhou Zhu; Francisco J. Barba] A
Authors to whom correspondence should be addressed.<&wdkj&>Department of Preventive Medicine and Public Health, Food Science, Toxicology and Forensic Medicine, Faculty of Pharmacy, University of Valencia, 46100 Valencia, Spain<&wdkj&>Authors to whom correspondence should be addressed.<&wdkj&>National R&D Center for Se-Rich Agricultural Products Processing Technology, Hubei Engineering Research Center for Deep Processing of Green Se-Rich Agricultural Products, School of Modern Industry for Selenium Science and Engineering, Wuhan Polytechnic University, Wuhan 430205, China
语种:
英文
关键词:
Candida antarctica lipase B;enzymatic esterification;membrane separation;hesperidin lipophilization;bioinspired lipase immobilized membrane
期刊:
Antioxidants
ISSN:
2076-3921
年:
2022
卷:
11
期:
10
页码:
1906-
基金类别:
Research, formal analysis, data analysis, and writing—original draft, S.M.; methodology and investigation, S.L., Z.C., X.C., F.W., S.D., K.M., F.J.B. and W.Z.; funding acquisition and project management, Z.Z.; writing—review and editing, S.M., F.J.B., and Z.Z. All authors have read and agreed to the published version of the manuscript. This research was funded by the Outstanding Young and Middle-aged Science and Technology Innovation Team in Hubei Province (T2020012), Major Technology Innovation of Hubei Province (2019ABA113), National Natural Science Foundation of China (51908136 and 22178136), Key Research and Development Program of Hubei Province (2020BBA043) and “One Hundred-Talent Program” of Hubei Province, China.
机构署名:
本校为第一机构
院系归属:
硒科学与工程现代产业学院
摘要:
Lipophilization is a promising way to improve the bioavailability of flavonoids. However, the traditional enzymatic esterification methods are time-consuming, and present low yields and purity. Herein, a novel membrane-based lipophilization technology—bioinspired lipase immobilized membranes (BLIMs), including CAL-B@PES, CAL-B@PDA/PES and GA/CAL-B@PDA/PES— were fabricated to improve the antioxidant flavanone glycoside hesperidin lipophilization. Via reverse filtration, PDA coating and GA crosslinking, Candida antarctica lipase B (CAL-B) was s...

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