期刊论文

Zhang, Mingwei

英文

Carbohydrate Polymers

0144-8617

2020

229

115475

10.1016/j.carbpol.2019.115475

This work was supported by the National Key Research Project of China ( 2017YFC1601002 ), National Natural Science Foundation of China ( 31771979 ), Guangdong Provincial Science and Technology Project ( 2017A030313163 , 2018A050506050 ), and President Foundation of Guangdong Academy of Agricultural Sciences ( 201812B ). We thank LetPub ( www.letpub.com ) for its linguistic assistance during the preparation of this manuscript. Appendix A

本校为其他机构

The integrity of the intestinal mucosal barrier is important for the health of the host. In this study, longan pulp polysaccharides (LP) prevented the intestinal mucosal injury by increasing the expression of mucin 2, tight junction proteins zonulae occludens-1 (ZO-1), claudin-1, claudin-4, and adherens junction E-cadherin in cyclophosphamide-treated mice. To further identify the principle bioactive component of LP, four acidic polysaccharides (LPIa, LPIIa, LPIIIa, and LPIVa) were puri fi ed, and their intestinal protection activity in vitro was compared. LPIa, LPIIa, and LPIIIa displayed an a...