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Zinc Oxide Administration Relieves the Diarrhea of ETEC K88-Infected Piglets by Reducing Ileal Apoptosis and Maintaining Gut Microbial Balance

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成果类型:
期刊论文
作者:
Zhang, Yanyan;Liu, Jiale;Li, Muzi;Dong, Yi;Li, Zongyun;...
通讯作者:
Hou, YQ
作者机构:
[Dong, Yi; Wu, Tao; Li, Zongyun; Liu, Jiale; Hou, Yongqing; Wang, Lei; Li, Muzi; Zhao, Di; Yi, Dan; Zhang, Yanyan] Wuhan Polytech Univ, Engn Res Ctr Feed Prot Resources Agr Prod, Hubei Key Lab Anim Nutr & Feed Sci, Minist Educ, Wuhan 430024, Peoples R China.
通讯机构:
[Hou, YQ ] W
Wuhan Polytech Univ, Engn Res Ctr Feed Prot Resources Agr Prod, Hubei Key Lab Anim Nutr & Feed Sci, Minist Educ, Wuhan 430024, Peoples R China.
语种:
英文
关键词:
ETEC K88;diarrhea;gram-negative enterotoxin piglets;gut health;gut microbial;ileal apoptosis;pathogen-induced diarrhea
期刊:
Veterinary Sciences
ISSN:
2306-7381
年:
2025
卷:
12
期:
2
页码:
115
基金类别:
National Natural Science Foundation of China#&#&#U22A20514#&#&#32172763 National Key R&D Program of China#&#&#2022YFD130040302 Hubei Provincial Key R&D Program#&#&#2023BBB040 Research and Innovation Initiatives of WHPU#&#&#2024J04
机构署名:
本校为第一且通讯机构
院系归属:
动物科学与营养工程学院
摘要:
The impact of ZnO as a feed additive on growth-performance and intestinal function of Enterotoxigenic Escherichia coli (ETEC) K88-infected piglets remains unclear. Fecal scores of piglets in ETEC group were significantly increased compared to control group. ETEC K88 significantly damages the small intestine, including a reduction in villus height in the jejunum, duodenum, and ileum, and a decrease in total superoxide dismutase activity in the jejunum and catalase activity in the ileum and jejunum. Compared to control group, ETEC K88 infection s...

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