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Lycopene alleviates multiple-mycotoxin-induced toxicity by inhibiting mitochondrial damage and ferroptosis in the mouse jejunum

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成果类型:
期刊论文
作者:
Lin, Jia;Zuo, Cuige;Liang, Tianzeng;Huang, Yang;Kang, Ping;...
通讯作者:
Liu, Yulan(yulanflower@126.com)
作者机构:
[Zuo, Cuige; Liang, Tianzeng; Liu, Yulan; Huang, Yang; Lin, Jia; Kang, Ping; Xiao, Kan] Wuhan Polytech Univ, Hubei Collaborat Innovat Ctr Anim Nutr & Feed Saf, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Peoples R China.
通讯机构:
[Yulan Liu] H
Hubei Key Laboratory of Animal Nutrition and Feed Science, Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Wuhan Polytechnic University, Wuhan 430023, China
语种:
英文
期刊:
FOOD & FUNCTION
ISSN:
2042-6496
年:
2022
卷:
13
期:
22
页码:
11532-11542
基金类别:
This study was conducted with assistance from the National Natural Science Foundation of China (No. 32002346) and Wuhan Science and Technology Bureau (No. 2022020801010391).
机构署名:
本校为第一机构
院系归属:
动物科学与营养工程学院
摘要:
Multiple mycotoxins contamination in foods and feeds threatens human and animal health after they accumulate in the food chain, producing various toxic effects. The common mycotoxins contaimination in feeds are zearalenone (ZEN), deoxynivalenol (DON), and aflatoxin B1 (AFB1), but the effects of their co-exposure on the jejunum are not well understood. Lycopene (LYC) has been reported to have antioxidant activity that alleviates jejunal damage. In this study, we investigated the possible role of LYC as a treatment to mitigate the combined effect...

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