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Dietary Supplementation with Lactobacillus casei Alleviates Lipopolysaccharide-Induced Liver Injury in a Porcine Model

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成果类型:
期刊论文
作者:
Zhao, Di;Wu, Tao;Yi, Dan;Wang, Lei;Li, Peng;...
通讯作者:
Hou, Yongqing
作者机构:
[Wu, Tao; Hou, Yongqing; Wang, Lei; Li, Peng; Wu, Guoyao; Zhao, Di; Yi, Dan; Zhang, Junmei] Wuhan Polytech Univ, Hubei Collaborat Innovat Ctr Anim Nutr & Feed Saf, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Hubei, Peoples R China.
[Wu, Guoyao] Texas A&M Univ, Dept Anim Sci, College Stn, TX 77843 USA.
通讯机构:
[Hou, Yongqing] W
Wuhan Polytech Univ, Hubei Collaborat Innovat Ctr Anim Nutr & Feed Saf, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Hubei, Peoples R China.
语种:
英文
关键词:
Lactobacillus casei;piglets;lipopolysaccharide;liver
期刊:
International Journal of Molecular Sciences
ISSN:
1422-0067
年:
2017
卷:
18
期:
12
基金类别:
National Key R&D Program of China [2016YFD0501210, 2017YFD0500505]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31372319, 31572416, 31402084]; Hubei Provincial Technology and Innovation Program [2016ABA121, 2017AHB062]; Natural Science Foundation of Hubei ProvinceNatural Science Foundation of Hubei Province [2016CFA070]; Hubei Hundred Talent Program [2014-67015-21770]; Agriculture and Food Research Initiative of the USDA National Institute of Food and Agriculture [2014-67015-21770]; Texas AgriLife Research [H-82000]
机构署名:
本校为第一且通讯机构
院系归属:
动物科学与营养工程学院
摘要:
This study aims to determine whether Lactobacillus casei (L. casei) could relieve liver injury in piglets challenged with lipopolysaccharide (LPS). Piglets were randomly allocated into one of the three groups: control, LPS, and L. casei. The control and LPS groups were fed a corn- and soybean meal-based diet, whereas the L. casei group was fed the basal diet supplemented with 6 × 106 cfu/g L. casei. On Day 31 of the trial, piglets in the LPS and L. casei groups receivedintraperitoneal administration of LPS (100 μg/kg body weight), while the c...

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