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Dietary Supplementation with Probiotics Alleviates Intestinal Injury in LPS-Challenged Piglets

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成果类型:
期刊论文
作者:
Zhao, Di;Zhang, Junmei;Yi, Dan;Wu, Tao;Dou, Maoxin;...
通讯作者:
Hou, YQ
作者机构:
[Wu, Tao; Hou, Yongqing; Dou, Maoxin; Wang, Lei; Zhao, Di; Zhang, Junmei; Yi, Dan] Wuhan Polytech Univ, Engn Res Ctr Feed Prot Resources Agr By Prod, Hubei Key Lab Anim Nutr & Feed Sci, Minist Educ, Wuhan 430023, Peoples R China.
通讯机构:
[Hou, YQ ] W
Wuhan Polytech Univ, Engn Res Ctr Feed Prot Resources Agr By Prod, Hubei Key Lab Anim Nutr & Feed Sci, Minist Educ, Wuhan 430023, Peoples R China.
语种:
英文
关键词:
Lactobacillales spp.;Bacillus;lipopolysaccharide;intestinal function
期刊:
International Journal of Molecular Sciences
ISSN:
1661-6596
年:
2025
卷:
26
期:
15
页码:
7646-
基金类别:
Conceptualization, Y.H.; methodology, Y.H., D.Y. and T.W.; validation, D.Z. and M.D.; formal analysis, D.Z., J.Z. and M.D.; investigation, M.D., D.Z., J.Z. and L.W.; resources, Y.H., D.Y. and T.W.; data curation, D.Z., J.Z., M.D. and L.W.; writing—original draft preparation, D.Z. and J.Z.; writing—review and editing, Y.H. and D.Y.; visualization, D.Z.; supervision, Y.H.; project administration, Y.H.; funding acquisition, Y.H., D.Y. and T.W. All authors have read and agreed to the published version of the manuscript. This research was funded by the National Natural Science Foundation of China (32172763, U22A20514), the National Key R&D Program of China (2022YFD130040302), the Hubei Provincial Key R&D Program (2021BBA083), and Hubei Important Science and Technology Project (2024BBA004).
机构署名:
本校为第一且通讯机构
院系归属:
动物科学与营养工程学院
摘要:
This study aimed to assess whether dietary supplementation with probiotics could alleviate intestinal injury in lipopolysaccharide (LPS)-challenged piglets. Healthy weaned piglets were randomly allocated to four individual groups (n = 6): (1) a control group; (2) an LPS group; (3) an LPS + Lactobacillus group; and (4) an LPS + Bacillus group. The control and LPS groups received a basal diet, while the probiotic groups were provided with the same basal diet supplemented with 6 × 10(6) cfu/g of Lactobacillus casei (L. casei) or a combination of ...

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