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Site-specific modification of N-terminal α-amino groups of succinylated collagen

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成果类型:
期刊论文
作者:
Zhang, Juntao;Sui, Peishan;Yang, Wendian;Shirshin, Evgeny A.;Zheng, Mingming;...
通讯作者:
Haibo Wang
作者机构:
[Xu, Chengzhi; Sui, Peishan; Wei, Benmei; Yang, Wendian; Wang, Haibo; Zhang, Juntao; Zheng, Mingming] Wuhan Polytech Univ, Sch Chem & Environm Engn, Wuhan, Hubei, Peoples R China.
[Shirshin, Evgeny A.] Moscow MV Lomonosov State Univ, Dept Phys, Leninskie Gory 1-2, Moscow 119991, Russia.
[Zheng, Mingming] Chinese Acad Agr Sci, Oil Crops Res Inst, Key Lab Oilseeds Proc, Hubei Key Lab Lipid Chem & Nutr,Minist Agr, Wuhan, Hubei, Peoples R China.
通讯机构:
[Haibo Wang] S
School of Chemical and Environmental Engineering, Wuhan Polytechnic University, Wuhan, Hubei, China
语种:
英文
关键词:
PNIPAAm;Site-specific modification;Succinylated collagen
期刊:
International Journal of Biological Macromolecules
ISSN:
0141-8130
年:
2023
卷:
225
页码:
310-317
基金类别:
CRediT authorship contribution statement Juntao Zhang: Conceptualization, Methodology, Writing, acquisition, Supervision, Project administration. Peishan Sui: Writing - original draft. Wendian Yang: Data curation. Evgeny A. Shirshin: Revision. Mingming Zheng: Formal analysis. Benmei Wei: Investigation. Chengzhi Xu: Resources. Haibo Wang: acquisition, Supervision, Project administration.
机构署名:
本校为第一机构
院系归属:
化学与环境工程学院
摘要:
Polymer based protein engineering provides an attractive strategy to endow novel properties to protein and overcome the inherent limitations of both counterparts. The exquisite control of site and density of attached polymers on the proteins is crucial for the bioactivities and properties of the protein-polymer bioconjugates, but is still a challenge. Collagen is the major structural protein in extracellular matrix of animals. Based on the advancements of polymer-based protein engineering, collagen bioconjugates has been widely fabricated and a...

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