期刊论文

Li, J.

中文

精细石油化工

1003-9384

2007

24

1

34-37

10.3969/j.issn.1003-9384.2007.01.011

湖北省教育厅科研资助项目（2002D01002）。；

本校为第一且通讯机构

以苯甲醛和丙二酸为原料，吡啶为催化剂，利用Knoevenagel反应合成肉桂酸，从而降低了反应温度，提高了收率和产物纯度，简化了合成工艺。同时通过正交实验探讨了不同工艺参数如反应物配比、反应时间、催化剂种类和用量等对肉桂酸收率的影响，确定的最佳工艺条件为：以吡啶为催化剂，n（苯甲醛）：n（丙二酸）=1：3，催化剂用量0．02mol，反应时间为90min，肉桂酸收率可达90％。

Cinnamic acid was synthesized from benzaldehyde and malonic acid by Knoevenagel reaction with pyridine as catalyst. The effects of various technical parameters such as the reactant proportions, reaction time, the types and the amount of the catalyst on the yield of the products were investigated by orthogonally designed experiments. Under the optimal conditions： O. 02 mol pyridine, molar ratio of benzaldehyde to malonic acid 1 ： 3 and r...