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Comparative transcriptome analysis of Pseudomonas putida KT2440 revealed its response mechanisms to elevated levels of zinc stress

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成果类型:
期刊论文
作者:
Peng, Jun;Miao, Lihong;Chen, Xi;Liu, Pulin*
通讯作者:
Liu, Pulin
作者机构:
[Peng, Jun; Liu, Pulin; Miao, Lihong] Wuhan Polytech Univ, Coll Biol & Pharmaceut Engn, Wuhan, Hubei, Peoples R China.
[Chen, Xi] Chinese Acad Sci, Wuhan Inst Virol, Wuhan, Hubei, Peoples R China.
通讯机构:
[Liu, Pulin] W
Wuhan Polytech Univ, Coll Biol & Pharmaceut Engn, Wuhan, Hubei, Peoples R China.
语种:
英文
关键词:
Pseudomonas putida;basic metabolism;membrane homeostasis;metal transport;oxidative stress;stress response;transcriptome analysis;zinc
期刊:
Frontiers in Microbiology
ISSN:
1664-302X
年:
2018
卷:
9
期:
JUL
页码:
1669
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31700100]; Hubei Provincial Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [2017CFB207]
机构署名:
本校为第一且通讯机构
院系归属:
生命科学与技术学院
摘要:
The whole-genome transcriptional response of Pseudomonas putida KT2440 to stress-inducing concentrations of zinc was analyzed in this study by RNA sequencing to thoroughly investigate the bacterial cell response to zinc toxicity. The data revealed that different levels of zinc stress strongly affected the transcription of genes from the following categories: metal transport genes, genes involved in membrane homeostasis, oxidative-stress-responding genes, and genes associated with basic cellular metabolism. At the lowest zinc dose, only several ...

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