Transcriptome Analysis Reveals Regulation of Gene Expression for Lipid Catabolism in Young Broilers by Butyrate Glycerides

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成果类型：

期刊论文

作者：

Yin, Fugui;Yu, Hai;Lepp, Dion;Shi, Xuejiang;Yang, Xiaojian;...

通讯作者：

Gong, Joshua

作者机构：

[Yang, Xiaojian; Lepp, Dion; Gong, Joshua; Yin, Fugui; Yu, Hai] Agr & Agri Food Canada, Guelph Res & Dev Ctr, Guelph, ON, Canada.

[Shi, Xuejiang] UHN MSH Gene Profiling Facil, Next Generat Sequencing Platforms, Clin Genom Ctr, Toronto, ON, Canada.

[Nie, Shaoping; Hu, Jielun] Nanchang Univ, State Key Lab Food Sci & Technol, Nanchang, Jiangxi, Peoples R China.

[Leeson, Steve] Univ Guelph, Dept Anim & Poultry Sci, Guelph, ON, Canada.

[Yang, Chengbo] Univ Manitoba, Dept Anim Sci, Winnipeg, MB, Canada.

通讯机构：

[Gong, Joshua] A

Agr & Agri Food Canada, Guelph Res & Dev Ctr, Guelph, ON, Canada.

语种：

英文

关键词：

Jejunum;Diet;Adipose tissue;Fatty acids;Lipid metabolism;Gene expression;Glycerides;Lipids

期刊：

PLOS ONE

ISSN：

1932-6203

年：

2016

卷：

期：

页码：

e0160751

DOI：

10.1371/journal.pone.0160751

基金类别：

Agriculture and Agri-Food Canada's Poultry Cluster IIAgriculture & Agri Food Canada [J-000264]; China Scholarship Council through the MOE-AAFC Ph.D. Research ProgramChina Scholarship Council; Agriculture & Agri-Food Canada (AAFC)Agriculture & Agri Food Canada; Canadian Poultry Research Council through AAFCAAFCip Council through the MOE-AAFC Ph.D. Research Program

机构署名：

本校为其他机构

院系归属：

动物科学与营养工程学院

摘要：

BACKGROUND & AIMS: Butyrate has been shown to potently regulate energy expenditure and lipid metabolism in animals, yet the underlying mechanisms remain to be fully understood. The aim of this study was to investigate the molecular mechanisms of butyrate (in the form of butyrate glycerides, BG)-induced lipid metabolism at the level of gene expression in the jejunum and liver of broilers. METHODOLOGY/PRINCIPAL FINDINGS: Two animal experiments were included in this study. In Experiment 1, two hundred and forty male broiler chickens were equally allocated into two groups: 1) basal diet (BD), 2) B...

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Transcriptome Analysis Reveals Regulation of Gene Expression for Lipid Catabolism in Young Broilers by Butyrate Glycerides

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