Effects of Supplementation of Branched-Chain Amino Acids to Reduced-Protein Diet on Skeletal Muscle Protein Synthesis and Degradation in the Fed and Fasted States in a Piglet Model

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zheng, Liufeng;Wei, Hongkui;He, Pingli;Zhao, Shengjun;Xiang, Quanhang;...

通讯作者：

Peng, Jian

作者机构：

[Zheng, Liufeng; Wei, Hongkui; Xiang, Quanhang; Pang, Jiaman; Peng, Jian] Huazhong Agr Univ, Coll Anim Sci & Technol, Dept Anim Nutr & Feed Sci, Wuhan 430070, Peoples R China.

[Wei, Hongkui; Peng, Jian] Cooperat Innovat Ctr Sustainable Pig Prod, Wuhan 430070, Peoples R China.

[He, Pingli] China Agr Univ, Coll Anim Sci & Technol, State Key Lab Anim Nutr, Beijing 100094, Peoples R China.

[Zhao, Shengjun] Wuhan Polytech Univ, Dept Feed Sci, Wuhan 430023, Peoples R China.

通讯机构：

[Peng, Jian] H

[Peng, Jian] C

Huazhong Agr Univ, Coll Anim Sci & Technol, Dept Anim Nutr & Feed Sci, Wuhan 430070, Peoples R China.

Cooperat Innovat Ctr Sustainable Pig Prod, Wuhan 430070, Peoples R China.

语种：

英文

关键词：

branched-chain amino acids;muscle protein degradation;muscle protein synthesis;piglets;alpha-ketoisocaproate

期刊：

Nutrients

ISSN：

2072-6643

年：

2017

卷：

期：

DOI：

10.3390/nu9010017

基金类别：

National Basic Research Program of China (973 Program)National Basic Research Program of China [2013CB127305]; Key Technology Research and Development Program of Hubei Province [2014ABB014, 2014ABC012]

机构署名：

本校为其他机构

院系归属：

动物科学与营养工程学院

摘要：

Supplementation of branched-chain amino acids (BCAA) has been demonstrated to promote skeletal muscle mass gain, but the mechanisms underlying this observation are still unknown. Since the regulation of muscle mass depends on a dynamic equilibrium (fasted losses-fed gains) in protein turnover, the aim of this study was to investigate the effects of BCAA supplementation on muscle protein synthesis and degradation in fed/fasted states and the related mechanisms. Fourteen 26-(Experiment 1) and 28-day-old (Experiment 2) piglets were fed reduced-pro...

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Effects of Supplementation of Branched-Chain Amino Acids to Reduced-Protein Diet on Skeletal Muscle Protein Synthesis and Degradation in the Fed and Fasted States in a Piglet Model

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