Dietary litchi pulp polysaccharides could enhance immunomodulatory and antioxidant effects in mice

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成果类型：

期刊论文

作者：

Huang, Fei;Zhang, Ruifen;Liu, Yang;Xiao, Juan;Liu, Lei;...

通讯作者：

Zhang, Mingwei;Liu, Dong

作者机构：

[Wei, Zhencheng; Huang, Fei; Liu, Yang; Xiao, Juan; Zhang, Ruifen; Liu, Lei; Zhang, Mingwei] Guangdong Acad Agr Sci, Guangdong Key Lab Agr Prod Proc, Sericultural & Agri Food Res Inst, Key Lab Funct Foods,Minist Agr, Guangzhou 510610, Guangdong, Peoples R China.

[Liu, Dong] Shenzhen Polytech, Shenzhen Key Lab Fermentat Purificat & Anal, Shenzhen 518055, Peoples R China.

[Yi, Yang] Wuhan Polytech Univ, Coll Food Sci & Engn, Wuhan 430023, Peoples R China.

[Liu, Dong] Shenzhen Polytech, Coll Appl Chem & Biotechnol, Shenzhen 518055, Peoples R China.

通讯机构：

[Zhang, Mingwei] G

[Liu, Dong] S

Guangdong Acad Agr Sci, Guangdong Key Lab Agr Prod Proc, Sericultural & Agri Food Res Inst, Key Lab Funct Foods,Minist Agr, Guangzhou 510610, Guangdong, Peoples R China.

Shenzhen Polytech, Coll Appl Chem & Biotechnol, Shenzhen 518055, Peoples R China.

语种：

英文

关键词：

Litchi pulp polysaccharides;Immunomodulatory activity;Antioxidant activity

期刊：

International Journal of Biological Macromolecules

ISSN：

0141-8130

年：

2016

卷：

页码：

1067-1073

DOI：

10.1016/j.ijbiomac.2016.08.021

基金类别：

Joint Fund of the NSFC and Guangdong Provincial Government [U1301211]; Guangdong Natural Science FoundationNational Natural Science Foundation of Guangdong Province [2016A030310321]; Basic Research Program of Shenzhen [JCYJ20140901162541286]; Applied Research and Development Project of Guangdong Province [20158020230005]; Guangdong Provincial Research Institutes Reform and Innovation Project [20168070701012]

机构署名：

本校为其他机构

院系归属：

食品科学与工程学院

摘要：

The purpose of this study was, to investigate the immunomodulatory and antioxidant activities of litchi pulp polysaccharides (LP) in cyclophosphamide (Cy)-induced mice. The administration of LP (50, 100 and 200 mg/kg/d) remarkably enhanced mesenteric lymph node cells proliferation and serum IgA. Moreover, IL-6, TNF-alpha, IgG and IgM levels in serum were significantly improved in a dose-dependent manner with LP treatment. Dietary LP induced systemic immune responses including stimulating the proliferation of splenocytes, balancing the ratio of spleen lymphocyte subsets, up-regulating the thymu...

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Dietary litchi pulp polysaccharides could enhance immunomodulatory and antioxidant effects in mice

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