Soy protein isolate was chemically modified by oxidation of H2O2. The effects of single factor variation such as dosgage of H2Q2, reaction temperature and time on modification efficiency were investigated, respectively. On the base of that, orthogonal tests were designed for optimization of parameters. The results illustrated that the dosage of H2O2 and reaction temperature were two key factors.The optimum parameters were that the dosage of H2O2(concentration 20% ) was 2.4 mL/g protein,...