版权说明 操作指南
首页 > 成果 > 详情

Investigation of the inhibition effect of 1,2,3,4,6-pentagalloyl-beta-D-glucose on gastric cancer cells based on a network pharmacology approach and experimental validation

认领
导出
Link by DOI
反馈
分享
QQ微信 微博
成果类型:
期刊论文
作者:
Bi, Jing-hui;Jiang, Yu-han;Ye, Shi-jie;Wu, Min-rui;Yi, Yang;...
通讯作者:
Wang, L.-M.
作者机构:
[Bi, Jing-hui; Wang, Hong-xun; Ye, Shi-jie; Wu, Min-rui; Jiang, Yu-han; Wang, Li-mei] Wuhan Polytech Univ, Coll Life Sci & Technol, Wuhan, Peoples R China.
[Yi, Yang] Wuhan Polytech Univ, Coll Food Sci & Engn, Wuhan, Peoples R China.
通讯机构:
[Wang, L.-M.] C
College of Life Science and Technology, China
语种:
英文
关键词:
gastric cancer;mechanism;network pharmacology;p53 signaling pathway;β-PGG
期刊:
FRONTIERS IN ONCOLOGY
ISSN:
2234-943X
年:
2022
卷:
12
页码:
934958
基金类别:
This work was supported by the Primary Research & Development Plan of Hubei Province (2020BBB074, 2020BBA046).
机构署名:
本校为第一机构
院系归属:
食品科学与工程学院
生命科学与技术学院
摘要:
BackgroundGastric cancer (GC) is ranked as the third leading cause of cancer-related mortality worldwide. 1,2,3,4,6-Pentagalloyl-β-D-glucose (β-PGG) has various pharmacological activities and has been shown to suppress cancer development. However, the mechanism by which β-PGG inhibits gastric cancer has not been elucidated.ObjectiveThis study explored the potential targets and mechanism of β-PGG in GC using the network pharmacology approach combined with in-vitro experiments.MethodsThe PharmMapper software was used to predict the potential ...

反馈

验证码:
看不清楚,换一个
确定
取消

成果认领

标题:
用户 作者 通讯作者
请选择
请选择
确定
取消

提示

该栏目需要登录且有访问权限才可以访问

如果您有访问权限,请直接 登录访问

如果您没有访问权限,请联系管理员申请开通

管理员联系邮箱:yun@hnwdkj.com