Protein-Bound Anthocyanin Compounds of Purple Sweet Potato Ameliorate Hyperglycemia by Regulating Hepatic Glucose Metabolism in High-Fat Diet/Streptozotocin-Induced Diabetic Mice

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成果类型：

期刊论文

作者：

Jiang, Tian;Shuai, Xiaoyan;Li, Jia;Yang, Ning;Deng, Li;...

通讯作者：

He, Jingren

作者机构：

[Deng, Li; He, Yi; Li, Jia; Li, Shuyi; Shuai, Xiaoyan; Jiang, Tian; Yang, Ning; He, Jingren] Wuhan Polytech Univ, Sch Food Sci & Engn, Wuhan 430023, Peoples R China.

[He, Jingren] Hubei Key Lab Proc & Transformat Agr Prod, Wuhan 430023, Peoples R China.

[Guo, Heng] Yun Hong Grp Co Ltd, Wuhan 430206, Peoples R China.

[Li, Yubao] Wuhan 1 Hosp, Dept Pharm, Wuhan 430030, Peoples R China.

通讯机构：

[He, Jingren] W

[He, Jingren] H

Wuhan Polytech Univ, Sch Food Sci & Engn, Wuhan 430023, Peoples R China.

Hubei Key Lab Proc & Transformat Agr Prod, Wuhan 430023, Peoples R China.

语种：

英文

关键词：

Dietary supplements;Enzymes;Food products;Food storage;Genes;Glucose;Mammals;Medical problems;Metabolism;AMP-activated protein kinase;free anthocyanin compounds;Glucose transporters;Glucose-6-phosphatase;Hypoglycemic effect;Phosphoenolpyruvate carboxykinase;Phosphofructokinase;Purple sweet potatoes;Anthocyanins;anthocyanin;antidiabetic agent;glucose;plant extract;plant protein;adverse event;animal;chemistry;drug effect;experimental diabetes mellitus;human;hyperglycemia;Institute for Cancer Research mouse;lipid diet;liver;male;metabolism;mouse;plant tuber;sweet potato;Animals;Anthocyanins;Diabetes Mellitus, Experimental;Diet, High-Fat;Glucose;Humans;Hyperglycemia;Hypoglycemic Agents;Ipomoea batatas;Liver;Male;Mice;Mice, Inbred ICR;Plant Extracts;Plant Proteins;Plant Tubers

期刊：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

ISSN：

0021-8561

年：

2020

卷：

期：

页码：

1596-1608

DOI：

10.1021/acs.jafc.9b06916

基金类别：

The authors would like to thank the financial support from the Science and Technology Support Program of Hubei Province, China (2015BHE015). We also appreciate the support of the International Cooperation Research Funding granted by the Ministry of Science and Technology of China (2014DFG32310) and the National Natural Science Foundation of China (31371727).

机构署名：

本校为第一且通讯机构

院系归属：

食品科学与工程学院

摘要：

Purple sweet potato is known as a rich source of protein and anthocyanins. Anthocyanins can form complexes with protein present in food products through non-covalent forces or covalent bonds during processing, transportation, and storage as their protein affinity. We evaluated the hypoglycemic effects of protein-bound anthocyanin compounds of purple sweet potato (p-BAC-PSP) and free anthocyanin compounds of purple sweet potato (FAC-PSP) in high-fat diet/streptozotocin-induced diabetic mice. The results showed that administration of both p-BAC-P...

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Protein-Bound Anthocyanin Compounds of Purple Sweet Potato Ameliorate Hyperglycemia by Regulating Hepatic Glucose Metabolism in High-Fat Diet/Streptozotocin-Induced Diabetic Mice

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