期刊论文

Effects of Tributyrin on Gut Barrier Function of Acetic Acid-treated Piglets

中文

中国畜牧兽医

1671-7236

2018

45

9

2440-2446

10.16431/j.cnki.1671-7236.2018.09.012

国家重点研发计划课题“畜禽应激综合征防控技术研究”(2016YFD0501210)。

本校为第一机构

本试验旨在研究三丁酸甘油酯（TB）对乙酸（ACA）刺激仔猪小肠黏膜生长和肠道屏障功能的影响。试验选用18头体重接近、健康的28日龄断奶仔猪（杜×长×大）,随机分为3个处理:对照组、乙酸组和TB组,每个处理6个重复,每个重复1头猪。试验期为21d。试验期内对照组和乙酸组饲喂基础日粮,TB组饲喂基础日粮+0.1%TB。于试验第15天清晨,乙酸组和TB组仔猪直肠灌注10mL 10%乙酸,对照组直肠灌注相应剂量的灭菌生理盐水。于试验第18、21天清晨前腔静脉采血,测定血浆二胺氧化酶（DAO）活力;第21天屠宰取样,取空肠、回肠等组织样品,测定仔猪肠道形态结构、肠道黏膜损伤相关基因mRNA水平等指标。结果表明:（1）...

This study was conducted to study the effect of tributyrin(TB)on small intestine mucosal growth and gut barrier function of acetic acid(ACA)-treated piglets.Eighteen crossbred healthy piglets(Ducoc×Landrace×Yorkshire,28 days old)were randomly allocated into three treatment groups(control,ACA and TB).The pigs in control and ACA groups were fed basal diet,and TB group was fed the basal diet supplemented with 0.1%TB.On day 15 of the trial,ACA and TB groups were intracolonically administrated with 10 mL of 10%ACA solution,control group were given...