In order to obtain high quality natto, using the superior quality soybean as raw material and natto kinase content and mucus yield as evaluation index, the effects of initial water content, inoculum, fermentation temperature, time on natto kinase content and mucus yield were researched. According to the results of single factor experiments, natto solid-state fermentation technology was optimized by orthogonal rotation combination design. The optimum parameters of natto solid-state fermentation technology were initial water content 51%, inoculum...