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Cannabis Seed Oil Alleviates Experimental Atherosclerosis by Ameliorating Vascular Inflammation in Apolipoprotein-E-Deficient Mice

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成果类型:
期刊论文、会议论文
作者:
Huang, Wenjing;Zeng, Zhujun;Lang, Yan;Xiang, Xia;Qi, Gaofu;...
通讯作者:
Wenjing Huang<&wdkj&>Gaofu Qi<&wdkj&>Gan Lu<&wdkj&>Xiangliang Yang
作者机构:
College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan, Hubei 430023, People’s Republic of China
[Lang, Yan; Lu, Gan; Yang, Xiangliang] National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, People’s Republic of China
[Zeng, Zhujun; Qi, Gaofu] College of Life Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, People’s Republic of China
[Xiang, Xia] Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan, Hubei 430062, People’s Republic of China
[Huang, Wenjing] College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan, Hubei 430023, People’s Republic of China<&wdkj&>National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, People’s Republic of China
通讯机构:
[Wenjing Huang; Gaofu Qi] C
[Gan Lu; Xiangliang Yang] N
College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan, Hubei 430023, People’s Republic of China<&wdkj&>National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, People’s Republic of China<&wdkj&>National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, People’s Republic of China<&wdkj&>College of Life Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, People’s Republic of China
语种:
英文
关键词:
Cannabis seed oil;anti-inflammation;antioxidation;arterial lipid deposition;atherosclerosis;endothelial cell integrity
期刊:
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
ISSN:
0021-8561
年:
2021
卷:
69
期:
32
页码:
9102-9110
会议名称:
5th International Symposium on Lipid Science and Health (ISLSH)
会议时间:
OCT, 2020
会议地点:
Wuhan, PEOPLES R CHINA
机构署名:
本校为第一机构
院系归属:
食品科学与工程学院
摘要:
In recent decades, epidemiological, clinical, and experimental studies have demonstrated that a diet with antioxidant or anti-inflammatory function plays a central role in the prevention of atherosclerosis (AS). The purpose of this study was to explore the effects of Cannabis seed oil (CO) administration on in vitro antioxidant capacity as well as blood lipid profiles, lipid peroxidation, inflammatory response, and endothelial cell integrity. Female ApoE(-/-) mice were fed a high-cholesterol diet and administrated with CO or phosphate-buffered ...

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