Effects of Clostridium butyricum and Its Extracellular Vesicles on Intestinal Fungal Community Structure of Mice with Colitis [丁酸梭菌及其胞外囊泡对结肠炎小鼠肠道真菌菌群结构的影响]

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成果类型：

期刊论文

作者：

彭浩;任莹;马灵燕;吕文涛;陈渠;...

通讯作者：

Xiao, Y.

作者机构：

[任莹] Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan, 430023, China

[马灵燕; 陈渠; 杨华; 肖英平; Lyu W.] State Key Laboratory for Managing Biotic and Chemical Threats of the Quality and Safety of Agro-Products, Institute of Agro-Product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, China

[彭浩] Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan, 430023, China, State Key Laboratory for Managing Biotic and Chemical Threats of the Quality and Safety of Agro-Products, Institute of Agro-Product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, China

通讯机构：

[Xiao, Y.] S

State Key Laboratory for Managing Biotic and Chemical Threats of the Quality and Safety of Agro-Products, China

语种：

中文

关键词：

丁酸梭菌;胞外囊泡;结肠炎;小鼠;真菌菌群结构

关键词(英文)：

Clostridium butyricum;colitis;extracellular vesicles;fungal community structure;mice

期刊：

动物营养学报

ISSN：

1006-267X

年：

2023

卷：

期：

页码：

4686-4696

DOI：

10.12418/CJAN2023.435

基金类别：

国家自然科学基金项目(31972999)。

机构署名：

本校为第一机构

院系归属：

动物科学与营养工程学院

摘要：

本试验旨在研究丁酸梭菌及其胞外囊泡对小鼠结肠炎的缓解作用以及对肠道真菌结构的影响。试验选用8周龄雄性C57BL/6J小鼠24只,随机分为4组,每组6只。Control组、DSS组、CB组和EV组分别给予正常饮水并灌胃20...展开更多本试验旨在研究丁酸梭菌及其胞外囊泡对小鼠结肠炎的缓解作用以及对肠道真菌结构的影响。试验选用8周龄雄性C57BL/6J小鼠24只,随机分为4组,每组6只。Control组、DSS组、CB组和EV组分别给予正常饮水并灌胃200μL/d生理盐水、3%葡聚糖硫酸钠(DSS)饮水并灌胃200μL/d生理盐水、3%DSS饮水并灌胃200μL/d丁酸梭菌溶液(5×108CFU/mL)、3%DSS饮水并灌胃50μg/d丁酸梭菌胞外囊泡(溶于200...

摘要(英文)：

The aim of this study was to investigate the alleviation effect of Clostridium butyricum and its extra⁃cellular vesicles on colitis of mice and its impact on the intestinal fungal community structure.Twenty⁃four 8⁃week⁃old male C57BL/6J mice were randomly divided into 4...MORE The aim of this study was to investigate the alleviation effect of Clostridium butyricum and its extra⁃cellular vesicles on colitis of mice and its impact on the intestinal fungal community structure.Twenty⁃four 8⁃week⁃old male C57BL/6J mice were randomly divided ...

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