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Metabolism, Nutrition, and Redox Signaling of Hydroxyproline

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成果类型:
期刊论文
作者:
Wu, Zhenlong;Hou, Yongqing;Dai, Zhaolai;Hu, Chien-An A.;Wu, Guoyao*
通讯作者:
Wu, Guoyao
作者机构:
[Wu, Zhenlong; Dai, Zhaolai; Wu, Guoyao] China Agr Univ, State Key Lab Anim Nutr, Beijing, Peoples R China.
[Hou, Yongqing; Wu, Guoyao; Hu, Chien-An A.] Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Hubei Collaborat Innovat Ctr Anim Nutr & Feed Saf, Wuhan, Hubei, Peoples R China.
[Hu, Chien-An A.] Univ New Mexico, Hlth Sci Ctr, Dept Biochem & Mol Biol, Albuquerque, NM 87131 USA.
[Wu, Guoyao] Texas A&M Univ, Dept Anim Sci, College Stn, TX 77843 USA.
通讯机构:
[Wu, Guoyao] T
Texas A&M Univ, Dept Anim Sci, College Stn, TX 77843 USA.
语种:
英文
关键词:
antioxidant;health;hydroxyproline;nutrition;oxidase;proline
期刊:
ANTIOXIDANTS & REDOX SIGNALING
ISSN:
1523-0864
年:
2019
卷:
30
期:
4
页码:
674-682
基金类别:
National Basic Research Program of ChinaNational Basic Research Program of China [2013CB127302]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31172217, 31272450, 31272451, 31572412]; Chinese Universities Scientific Fund [2013RC002, 2015DK001]; Program for New Century Excellent Talents in UniversityProgram for New Century Excellent Talents in University (NCET) [NCET-120522]; 111 ProjectMinistry of Education, China - 111 Project [B16044]; Program for Beijing Municipal Excellent Talents; Agriculture and Food Research Initiative from the USDA National Institute of Food and Agriculture [2014-67015-21770, 2015-67015-23276]; Texas A&M AgriLife Research [H-8200]
机构署名:
本校为其他机构
院系归属:
动物科学与营养工程学院
摘要:
SIGNIFICANCE: Hydroxyproline is a structurally and physiologically important imino acid in animals. It is provided from diets and endogenous synthesis, and its conversion into glycine enhances the production of glutathione, DNA, heme, and protein. Furthermore, oxidation of hydroxyproline by hydroxyproline oxidase (OH-POX) plays an important role in cell antioxidative reactions, survival, and homeostasis. Understanding the mechanisms whereby hydroxyproline participates in metabolism and cell signaling can improve the nutrition and health of animals and humans. Recent Advances: Hydroxyproline is...

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