The supercritical CO_2 fluid extraction(SFE–CO_2) technology of Cornus officinalis seeds oil was studied. On the base of single factor test results,response surface methods were used to optimize the method of extraction Cornus officinalis seeds oil by supercritical CO_2 fluid. The optimal conditions for getting Cornus officinalis seeds oil were that extraction pressure was 41.5 MPa,extraction temperature was 37 ℃,and extraction time was 2.5 h. Under these conditions,the yield of oil was 39.85 %. The technology provided theoretical basis for...